Need for diurnal variation of intraocular pressure testing in eyes with pseudoexfoliation

Swetha Sara, Philip (2007) Need for diurnal variation of intraocular pressure testing in eyes with pseudoexfoliation. Masters thesis, Christian Medical College, Vellore.

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Abstract

INTRODUCTION: Glaucoma is the second leading causes of blindness globally today.[1] In India it is the third most common cause of blindness. It is estimated that glaucoma affects 12 million in India and is responsible for 12.8% of the blindness in the country. Glaucoma affects people of all ages producing serious health and economic consequences. In nearly all cases blindness from glaucoma is preventable if the disease is detected early and proper treatment is implemented. AIM: 1. To record the diurnal variation in intraocular pressure in eyes with pseudoexfoliation syndrome. 2. To record the disc findings and visual fields in eyes with pseudoexfoliation syndrome. 3. To determine the usefulness of diurnal measurement of intraocular pressure compared to initial intraocular pressure in diagnosing pseudoexfoliation glaucoma. 4. To document the outcome of cataract surgery in patients with pseudoexfoliation in terms of intraocular pressure, disc appearance, visual improvement and field testing. 5. To use the above data to determine, if possible, the effect of cataract surgery on intraocular pressure in pseudoexfoliation syndrome and pseudoexfoliation glaucoma. MATERIALS AND METHODS This study was conducted in the Department of Ophthalmology, Christian Medical College from March 2005 to June 2006. TYPE OF STUDY: Prospective cohort study INCLUSION CRITERIA: All patients found to have pseudoexfoliation in one or both eyes on presentation, with or without evidence of glaucoma. EXCLUSION CRITERIA: Patients were excluded from the study if any one or more of the following was present: 1. Any patient who had previously undergone any intraocular surgery in the eye with pseudoexfoliation. 2. Any patients on anti-glaucoma medications or on topical or systemic steroids. 3. Any patient with a history of ocular trauma or a documented history of uveitis. 4. Any other ocular pathology apart from age-related cataract that could contribute to development of a secondary glaucoma, eg corneal scars suggestive of suppurative keratitis. CONCLUSIONS: 1. Recording diurnal variation of intraocular pressure in eyes with pseudoexfoliation does not provide any additional benefit compared to the initial presenting IOP. 2. Initial intraocular pressure recording is sufficient to diagnose glaucoma in eyes with pseudoexfoliation. Disc changes may provide an additional indication of advanced glaucoma. 3. Visual field recordings in patients with pseudoexfoliation presenting to an ophthalmology OPD were found to be unreliable due to the profound drop in visual acuity caused by cataract. 4. Cataract surgery was not shown to have any effect on intraocular pressure in eyes with pseudoexfoliation.

Item Type: Thesis (Masters)
Uncontrolled Keywords: pseudoexfoliation; diurnal variation; intraocular pressure testing
Subjects: MEDICAL > Ophthalmology
Depositing User: Devi S
Date Deposited: 17 Nov 2017 06:09
Last Modified: 17 Nov 2017 06:09
URI: http://repository-tnmgrmu.ac.in/id/eprint/3983

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