Kotteeswari, P S (2016) Comparative study of fasting plasma insulin level between normotensives and preeclamptic women. Masters thesis, Madras Medical College, Chennai.
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Abstract
OBJECTIVE: 1. To compare, the levels of fasting plasma insulin level in normotensive pregnant women and preeclamptic women. 2. To correlate the elevation of fasting insulin levels in relation to the severity of preeclampsia. STUDY DESIGN: Comparative Study. SETTING: Institute of Obstetrics &Gynaecology, Egmore, Chennai. STUDY POPULATION: 70 preeclampsia women as cases, 30 normotensive women as control. STUDY METHODS: A comparative study was conducted between September 2014-July 2015, who satisfied the inclusion criteria. Blood samples were collected and analysed by CLIA technique for fasting plasma insulin levels among both control and cases. RESULTS: Preeclampsia women had significantly higher fasting plasma insulin levels (n=70 mean 19.933 μunits/ml) then control (n=30 mean 2.2417μ units/ml p=<0.000 units) levels of fasting plasma insulin were directly proportional to the severity of the disease. Mild PE - 7.3571 μunits/ml, Severe PE -26.4954 μunits/ml, P<0.000vhs. CONCLUSIONS: In normal pregnancy the fasting plasma insulin level is increased especially during third trimester. In pregnancy complicated by preeclampsia an exaggeration of the insulin resistance is seen with the resultant hyperinsulinemia. The result of this study showed that hyperinsulinemia was directly proportiaonl to the severity of the disease.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Fasting Plasma Insulin levels ; Normotensives ; pregnancy ; Hyperinsulinemia ; Preeclampsia. |
| Subjects: | MEDICAL > Obstetrics and Gynaecology |
| Depositing User: | Subramani R |
| Date Deposited: | 15 Nov 2017 16:42 |
| Last Modified: | 15 Nov 2017 16:42 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/3957 |
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