Preethy, Chandran (2013) An Invitro Study to Assess the Absorption and Release of Chlorhexidine from Acrylic Resin Discs Immersed in it thereby Simulating Clinical Treatment of Oral Candidiasis. Masters thesis, Tamilnadu Government Dental College, Chennai.
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Abstract
AIM & OBJECTIVES: The aim of this study is to assess the absorption and release of Chlorhexidine from acrylic heat cure and light cure resin discs simulating treatment of oral candidiasis. MATERIALS&METHODS: 10mm discs of prepolymerised heat cure acrylic discs and light cure resin discs were immersed in Chlorhexidine solution for 10 hours, after which they are washed dried & placed in distilled water.20μl of this is subjected to High Performance Liquid Chromatography analysis for every one,three and fifth hour. After a week this is subjected to Scanning Electron Microscopy. RESULTS: In comparison to the standard release of Chlorhexidine at 2.48 and 2.85 min the samples of heat cure showed the similar peaks but the light cure discs containing urethane dimethacrylate and triethylene dimethacrylate released much less. CONCLUSION: The peaking of Chlorhexidine from samples suggest that the retention time and area of peak is less than that of standard but effective against denture induced stomatitis especially in patients who are immunocompromised, diabetics and on long term antibiotics.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Chlorhexidine ; High Performance Liquid Chromatography ; Scanning Electron Microscopy. |
| Subjects: | DENTAL > Prosthodontics and Crown and Bridge |
| Depositing User: | Subramani R |
| Date Deposited: | 15 Nov 2017 01:50 |
| Last Modified: | 15 Nov 2017 01:50 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/3945 |
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