Piranitha, J (2013) Evaluation of Serum Anticardiolipin Antibody in Chronic Periodontitis Patients with and Without Diabetes Mellitus. Masters thesis, J.K.K. Nataraja Dental College and Hospital, Komarapalayam.
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Abstract
AIMS AND OBJECTIVES: The aim of this present study was to evaluate serum anticardiolipin antibody (ACA) IgG and IgM in Chronic Periodontitis (CP) patients, Healthy controls, Type 2 Diabetes Mellitus and Chronic Periodontitis with Type 2 Diabetes Mellitus patients and to find out whether CP has its role to influence ACA levels in Type 2 Diabetes Mellitus patients. MATERIALS AND METHODS: Venous blood samples were collected from four groups in a clean and dry tubes. Serum was separated and stored until analysis. Anticardiolipin antibody ELISA kit (Enzyme Linked Immuno Sorbent Assay) was used to assess IgG and IgM ACA levels. The results were subjected to statistical analysis. RESULTS: Cardiolipin is one of the phospholipid present in the inner mitochondrial membrane. The results showed that ACA IgG levels were more in Chronic Periodontitis with Type 2 Diabetes Mellitus group compared to other three groups. The ACA IgM levels were low compared to other three groups. CONCLUSION: The results proved that CP has role to increase the ACA levels in Diabetes group and periodontal health is important to maintain diabetic patient’s health. Therefore, within the limitations of this study it can be concluded that CP is one of the risk factor for Diabetes Mellitus.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Anticardiolipin antibody ; Type 2 Diabetes Mellitus ; Chronic Periodontitis. |
| Subjects: | DENTAL > Periodontology |
| Depositing User: | Subramani R |
| Date Deposited: | 13 Nov 2017 17:35 |
| Last Modified: | 13 Nov 2017 17:35 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/3935 |
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