Clinical study of pre operative and intra operative predictors for posterior capsular opacification and the visual outcome

Venkatesan, C (2013) Clinical study of pre operative and intra operative predictors for posterior capsular opacification and the visual outcome. Masters thesis, Madurai Medical College, Madurai.

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Abstract

INTRODUCTION: Posterior capsular opacification also called as after cataract or secondary cataract which develop over the clear posterior lens capsule few months to few years after an uneventful cataract surgery. Opacification of the Posterior capsule is usually caused by the postoperative proliferation of lens epithelial cells in the capsular bag. It remains the most frequent complication of cataract –intraocular lens surgery. It was particularly more common and severe in the early days of IOL surgeries in the late 1970s and early 1980s. The incidence of posterior capsular opacification was around 25% to 50% during those days. With the advent of more recent advances in cataract surgery and modern intra ocular lenses reduced the frequency of posterior capsular opacifications but still they form the common complication after cataract surgeries. In addition to classic posterior capsular opacification post operatively, lens epithelial cell proliferation is also involved in the pathogenesis of anterior capsular opacification and fibrosis. AIM OF THE STUDY: The aim of the study is to analyse and determine the preoperative and intra operative risk factors associated with posterior capsular opacification. To study the different factors involved in PCO formation like : age, history of long standing steroid intake, cataractous lens grading, type of surgery, type of IOL and IOL position in relation to capsule and to analyse the visual outcome. MATERIALS AND METHODS: This study ‘A Clinical Study of Preoperative and Intra operative predictors for Posterior Capsular Opacification and the visual outcome’ was a prospective study done at ‘The department of Ophthalmology, Government Rajaji Hospital, Madurai’ during the months of July 2011 to October 2012. 60 cases were operated on between July 2011 to September 2011. These cases were followed up for 1 year from September 2011 to 0ctober 2012. SELECTION CRITERIA: Patients attending the Ophthalmology department outpatient clinic, Government Rajaji Hospital, Madurai with complaints of defective vision and who were noted to have cataractous lens changes. A total of 60 patients were recruited for the study. SUMMARY: 60 patients who had cataract were selected for study. Mean age of the patient was 42.6 years. The age of the patients ranged from 3 to 70 years. Out of this 27(45%) patients were males and 33 (55%) patients were females. Among the patients selected 10(16.5%) patients were below the age of 15 years. 18 (30%) patients had long standing intake of steroids and 32 patients had uncomplicated subcapsular cataracts. CONCLUSION: The aim of our study was to analyse and determine the preoperative and intraoperative risk factors associated with Posterior capsular opacification. By analysing the results after 1 year of follow up after the surgery following conclusions are drawn: Paediatric cataracts has a very high incidence of PCO formation which may severely affect the development of the child and may lead on to visual deprivation amblyopia later. This complication could be avoided by planning extra measures like primary posterior capsulorhexis with or without anterior vitrectomy during cataract surgery and IOL implantation. Steroid induced subcapsular cataracts has more incidence of PCO formation post operatively when compared to uncomplicated subcapsular cataract. Implantation of PMMA posterior chamber IOLs has more incidence of PCO formation when compared with Acrylic posterior chamber IOLs.

Item Type: Thesis (Masters)
Uncontrolled Keywords: pre operative; intra operative predictors; posterior capsular opacification; visual outcome
Subjects: MEDICAL > Ophthalmology
Depositing User: Devi S
Date Deposited: 19 Oct 2017 08:58
Last Modified: 19 Oct 2017 08:58
URI: http://repository-tnmgrmu.ac.in/id/eprint/3741

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