Gayathri, M (2012) Pharmacoeconomic Evaluation of Antidiabetic Agents: Societal Perspective. Masters thesis, J K K Nataraja College of Pharmacy, Komarapalayam.
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Abstract
Diabetes mellitus is a chronic potentially disabling disease commonly encountered by health care professionals that represents an important public health and clinical concern12, Diabetes mellitus is a costly disease, both for the patient and the health care provider due to its chronicity and multi-organ involvement which resulted in frequent visit and admission to health facilities11. Pharmacoeconomics is a part of the tool bag; Pharmacist can be used to improve the efficacy of his profession. It adopts and applies the principles & methodology of health economics to the field of pharmaceutical policy 34. The cost benefit analysis facilitates decision making regarding the implementing, withdrawing or continuing of a program. Net social gains or loss make it easy for making decisions. Furthermore, CEA studies facilitate comparisons between different programs with different outcomes, since all outcomes are converted into monetary values The large cost is associated with diabetes and its treatment is unsustainable of most health care systems and hence there is increasing use of economic evaluation as a tool to allocate resources. These evaluates can track the current costs and assess the future expenses and resources allocation, which leads to the improvement of the quality of healthcare 63. Decisions about what treatment should be available within a healthcare system have always been influenced by the resources available to pay for them Economics are an issue in diabetes care because patients require continues medication care, monitoring supplies and equipment, regular office appointments and patient self management education to prevent acute complications and to reduce the risk of long term complications. The aim of this study was to perform pharmacoeconomic evaluation of long term and clinical outcomes of patients receiving anti diabetic treatment and to compare the total direct medical costs with each drug treatment. This was a prospective study that included only the records of patient who received anti diabetic drugs to improve the quality of care and to improve the compliance of diabetes to the medical care provided. Objectives : To find the patient demographics of diabetic population, to assess their adherence to therapy and Quality of health care, to analyze their clinical data with ongoing therapy, to study the prescribing pattern of the antidiabetic drugs To analyze their cost of therapy & beneficence To compare the cost and benefits among each drug used for treatment. the present study was to perform pharmacoeconomic analysis of antidiabetic drugs in a diabetology outpatient setting. Out of a total number of 421 patients enrolled in this study, 407 patients were analyzed for demographic study and the cost minimization and cost effectiveness analysis was performed for 388 patients. The study has estimated the following results. Males are found to be more affected by diabetes than do with females, with an average age in the range of 51-60 years of age and 1-5 years of duration. Population within the range of 51-60 years and 1-5 years duration was found have increased percentage of non-vegetarians, Obese, Sedentary, Alcoholics and tobacco users either as smokers or as chewers with increased weight loss. Micro vascular complications such as Retinopathy, Foot ulcer, Nephropathy and Neuropathy was very common with patients under 51-60 years of age and 1-5 years of diabetes duration, whereas with 1-5 years of diabetic duration, Hypertension, Dyslipidemia, and Cardio vascular disease are common macro vascular complications with 61-70 years, 51-70 years and 51-60 years of age, but Peripheral vascular diseases was common with 6-10 years of duration and 51-60 years of age, Suffering and Physical activity restriction was much lower with 51-60 years of age and 1-5 years of duration, at the same time population with 1-5 years of duration had a mild to moderate suffering and physical activity restriction with 41-50 years and 51-60 years of age respectively. Severe suffering was noticed with 11-15 years of duration and 71-80 years of age, while physical activity restriction was severe among patients with 41-50 years of age and 1-5 years of duration. Increased numbers of patients were treated effectively with a combination of 2- drug combination therapy.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Pharmacoeconomic ; Antidiabetic Agents ; Societal Perspective. |
| Subjects: | PHARMACY > Pharmacy Practice |
| Depositing User: | Ravindran C |
| Date Deposited: | 06 Oct 2017 09:42 |
| Last Modified: | 18 Dec 2017 05:22 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/3595 |
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