A Histomorphological Study of Polyps and Polypoid Lesions of Gastrointestinal Tract with Special Reference to Colonic Neoplastic Polyps.

Shanthi, V (2013) A Histomorphological Study of Polyps and Polypoid Lesions of Gastrointestinal Tract with Special Reference to Colonic Neoplastic Polyps. Masters thesis, Madras Medical College, Chennai.

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Abstract

Polyps and polypoid lesions in the gastrointestinal tract may vary from asymptomatic incidental findings and benign harmless lesions to invasive malignancies. Various investigatory modalities are being developed and available in developing countries for screening and diagnosis of these lesions. The morphology of the polyps are well defined to delineate them from one another. A careful study of adenomatous polyps is needed in view of potential for malignant transformation. This study finds a high incidence of colonic adenomatous polyps with synchronous colonic malignancies. The study is hospital-based and may not represent the true incidence of the disease in the community. Hence, community based studies are essential to assess the prevalence and risk factors for adenomatous polyps. Though surveillance programs have been framed, it is imperative to establish cost effective screening guidelines so as to detect the lesions earlier. As most of the lesions are left-sided they would be more accessible with colonoscopy techniques. Genetic studies are needed to establish predictive and prognostic markers for malignant transformation of adenomatous polyps. Future studies should be community-based with assessment of possible etiological and/or risk factors.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Histomorphological; Polyps Polypoid Lesions; Gastrointestinal Tract; Special Reference; Colonic Neoplastic Polyps.
Subjects: MEDICAL > Pathology
Depositing User: Subramani R
Date Deposited: 23 Jun 2017 11:43
Last Modified: 27 Mar 2020 02:05
URI: http://repository-tnmgrmu.ac.in/id/eprint/358

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