Immuno Phenotypic Study of Childhood Lymphoma with Special References to Gastrointestinal Lymphoma.

Selvi, S (2013) Immuno Phenotypic Study of Childhood Lymphoma with Special References to Gastrointestinal Lymphoma. Masters thesis, Madras Medical College, Chennai.

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Abstract

Lymphomas Are Neoplasms Of The Immune System. Lymphomas Are Of Two Types, Namely, Hodgkin’s And Non Hodgkin’s Lymphoma (NHL). Malignant Cells Affecting The Organs Such As Gastrointestinal Tract, Brain And Skin Other Than Lymph Node Are Referred To As Extranodal Lymphoma. Extranodal Lymphomas Are Mainly Non Hodgkin’s Type Commonly Involving Gastrointestinal Tract. [1]Gastrointestinal Lymphoma Constitutes About 10-15% Of All Non Hodgkin’s Lymphoma And About 30-40% Of All Extranodal Lymphoma. Pediatric Lymphoma Differs From Adult Lymphoma Due To Their Differences In Target Cells And Exposure To Environmental Agents. Between 2007 To 2011, 30 Patients Presented With Intestinal Lymphoma In Children Hospital Whereas In Adults Stomach Is The Most Common Site. [2] Recently, Prognosis For Childhood Gastrointestinal Lymphoma Improves With Realization Because All Cases Are Disseminated At Diagnosis And Systemic Therapy Is Needed For Long Term Disease Free Survival. [3] The Aim Of This Thesis Is To Clarify The Clinicopathological Features Of Paediatric Gastrointestinal B Cell Lymphoma In Our Institution, To Identify The Preferred Lines Of Treatment, To Correlate With Outcome And Finally To Identify The Significant Prognostic Factors. Childhood Malignancies Fall Into A Smaller Number Of Categories, With Uniform Pathology, Immunophenotyping, Cytogenetic, Clinical Features, Response To Therapy And Relative Frequency. Prognosis Of Lymphoma Is Based Mainly On The Histological Type And Stage Of The Disease.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Immuno Phenotypic ; Childhood Lymphoma ; Special References ; Gastrointestinal Lymphoma.
Subjects: MEDICAL > Pathology
Depositing User: Subramani R
Date Deposited: 23 Jun 2017 11:44
Last Modified: 23 Jun 2017 11:44
URI: http://repository-tnmgrmu.ac.in/id/eprint/356

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