Avinash, Verma (2015) Formulation and Evaluation of Bi-layer Tablet of Metformin and Glimepiride. Masters thesis, R.V.S College of Pharmaceutical Sciences, Coimbatore.
|
Text
2601079avinashverma.pdf Download (1MB) | Preview |
Abstract
This study is to formulate Metformin and Glimepiride in Bi-layer tablet dosage form and evaluate different process Parameters. As Metformin and Glimepiride have more solubility and absorption in intestine. Literature survey reveals that several formulation methods of Bi-layer tablet such as Wet Granulation and Dry Granulation have been reported for Formulation of Metformin and Glimepiride. Most of reported methods for estimation of Metformin and Glimepiride are Wet Granulation. But the formulation has been developed by Direct Compression Method in place of Wet and Dry granulation To achieve this goal, various prototype trials were taken and evaluated with respect to the various quality parameters such as Bulk Density, Sieve Analysis, Drug Uniformity, and Dissolution. Presently many brands are available in market, but present study carried out for developing of Metformin and Glimepiride Bi-layer tablets as generic product, which is cheaper, safe and better than other marketed products.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Bi-layer Tablet; Metformin; Glimepiride |
| Subjects: | PHARMACY > Pharmaceutics |
| Depositing User: | Ravindran C |
| Date Deposited: | 27 Sep 2017 11:37 |
| Last Modified: | 20 Dec 2017 09:58 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/3400 |
Actions (login required)
 |
View Item |
