Amarnath, G (2016) A study in the incidence of Helicobacter pylori in cases of duodenal Ulcer perforation in Government Vellore Medical College. Masters thesis, Government Vellore Medical College, Vellore.
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Abstract
BACKGROUND: Most of the patients having chronic peptic ulcer disease are usually found to be infected with helicobacter pylori infection. Previously, when the ulcer goes for perforation, immediate acidreduction surgery was being done, as there was a high incidence of relapse of ulcers after a simple closure. But, since most of the ulcers are caused by H. pylori, eradication of these organisms reduces the recurrence of ulcers . The aim of our study was to study the incidence of Helicobacter pylori in cases of duodenal ulcer perforation. METHODS: Our study included 30 operated patients of duodenal ulcer perforation and the incidence of H. pylori was found from the biopsy taken from ulcer edge, using Rapid urease test & HPE. RESULTS: Among thirty patients, samples of 16 patients (53.3%) showed Positive for Helicobacter pylori in Rapid urease test (CLO TEST) and HPE. The p value calculated is < 0.05 which is found to be significant by chi square test. CONCLUSION: As Helicobacter pylori is the most common cause for duodenal ulcer perforation, anti-helicobacter pylori eradication regimen can be used in all cases of perforated duodenal ulcer to prevent the ulcer recurrence and to prevent acid reducing surgeries.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Helicobacter pylori ; duodenal Ulcer perforation ; Government Vellore Medical College ; Vellore. |
| Subjects: | MEDICAL > General Surgery |
| Depositing User: | Subramani R |
| Date Deposited: | 27 Sep 2017 03:50 |
| Last Modified: | 27 Sep 2017 03:50 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/3393 |
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