Association of Cholelithiasis, Choledocholithiasis and Hypothyroidism

Aishwarya, V L (2016) Association of Cholelithiasis, Choledocholithiasis and Hypothyroidism. Masters thesis, Thanjavur Medical College, Thanjavur.


Download (3MB) | Preview


INTRODUCTION: Thyroid disorder is a prevalent condition among adult population; however, it is frequently over looked.. Hypothyroidism causes low bile flow and sphincter of Oddi dysfunction and hence promotes gall stone formation. This study was done to substantiate the need for evaluating the thyroid status in patients presenting with cholelithiasis/ choledocholithiasis. AIMS: To study the prevalence of hypothyroidism in patients presenting with CHOLELITHIASIS/ CHOLEDHOCOLITHIASIS.To assess if thyroid profile is indicated in patients with biliary lithiasis. MATERIALS AND METHODS: This is an observational and prospective study. Method of sampling was non-random, purposive. 68 patients with USG evidence of cholelithiasis/ choledocholilithiasis, were evaluated with basic investigations and additionally thyroid function test was performed. The operation procedure and related per operative factors were observed directly and recorded. RESULTS: The operation procedure and related per operative factors were observed directly and recorded in the data collection sheet instantly. Age of these selected patients ranged from 20- 70 yrs, with mean age being 47.14 yrs. 32% were male patients and 68% were female patients. The male to female ratio is 1: 2. Females were the predominant group. Thyroid function test was performed in all 68 patients out of which, 18 patients (26.4%) were found to have hypothyroidism and the rest i.e. 50 patients were euthyroid. Of these 18 patients only 2 were known hypothyroid, rest 16 patients were newly diagnosed hypothyroid patients .Of these 18 patients, 16 patients were females rest were males. 50-70 yrs were the predominant group. More than 70% of the patients with hypothyroidism belong to this group. CONCLUSION: Evaluation of thyroid profile should be a part of general workup in patients with both cholelithiasis and choledocholithiasis especially in females above the age of 40yrs and patient should be treated with appropriate thyroid medications.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Hypothyroidism ; Cholelithiasis ; Choledocholithiasis.
Subjects: MEDICAL > General Surgery
Depositing User: Subramani R
Date Deposited: 27 Sep 2017 02:51
Last Modified: 27 Sep 2017 02:51

Actions (login required)

View Item View Item