A Comparative study of fine needle aspiration cytology versus fine needle non aspiration cytology Versus ultrasound guided fine needle aspiration cytology in the cytological evaluation of thyroid lesions

Sakthi Balan, M (2016) A Comparative study of fine needle aspiration cytology versus fine needle non aspiration cytology Versus ultrasound guided fine needle aspiration cytology in the cytological evaluation of thyroid lesions. Masters thesis, Stanley Medical College, Chennai.

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Abstract

AIMS & OBJECTIVES: To evaluate the efficacy of fine-needle non-aspiration cytology (FNNAC) with that of standard fine-needle aspiration cytology (FNAC) and USG guided FNAC of thyroid lesions as regards to cellular and hemorrhagic yield. MATERIALS AND METHODS: This study included 75 patients with thyroid lesions, out of which 25 cases underwent standard FNAC, 25 cases underwent FNNAC and 25 cases underwent USG guided FNAC. All the needle sampling procedures were performed by a single surgeon. The samples were then assessed cytologically using five parameters .i.e., background blood or clot,amount of cellular material,degree of cellular degeneration,degree of cellular trauma and retention of architecture and further categorised as unsuitable,adequate and diagnostically superior for cytological evaluation. RESULTS: Analysis showed that more number of diagnostically superior samples were obtained from FNNAC technique(72%) than that of standard FNAC(44%), whereas FNAC yielded more number of diagnostically adequate samples(52%) than that of FNNAC(24%), diagnostically inadequate samples were equal with both standard FNAC & FNNAC(4%). However, the diagnostic adequacy was equal in both FNNAC and standard FNAC techniques in thyroid lesions. On comparing FNNAC with that of USG guided FNAC, it was found that superior quality smears were more in FNNAC technique(72%vs 48%), but diagnostically adequate samples are more in USG guided FNAC than FNNAC(52% vs 24%). Also USG guided FNAC yielded fewer unsuitable smears. CONCLUSION: For highly vascular organs like thyroid , FNNAC is the preferred technique as there is better material with less admixture of blood by yielding more number of superior quality smears. The use of ultrasound enhances the diagnostic adequacy of FNAC by reducing the number of unsuitable smears obtained in smaller and cystic lesions.

Item Type: Thesis (Masters)
Uncontrolled Keywords: fine needle aspiration cytology ; fine needle non aspiration cytology ; ultrasound guided fine needle aspiration cytology ; cytological evaluation ; thyroid lesions ; Comparative study.
Subjects: MEDICAL > General Surgery
Depositing User: Subramani R
Date Deposited: 27 Sep 2017 02:40
Last Modified: 27 Sep 2017 02:40
URI: http://repository-tnmgrmu.ac.in/id/eprint/3382

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