Isolation and characterization of Helicobacter pylori in Gastro duodenal disease at a tertiary care hospital

Lavanya, J (2016) Isolation and characterization of Helicobacter pylori in Gastro duodenal disease at a tertiary care hospital. Masters thesis, PSG Institue of Medical Sciences and Research, Coimbatore.

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Abstract

Helicobacter pylori is a less studied bacteria in our country. Association of virulence factors like cagA and vacA subtypes to the disease manifestations and resistance profile to the commonly used first line drugs varies widely among the geographical regions. For effective treatment of patients, we need to know these epidemiological profiles of H.pylori for every individual region. Also, among various methods to detect H.pylori infection, Rapid urease test (RUT) has remained the most widely used one. The efficacy of the various commercial kits and in-house preparations must be evaluated before using them as a routine diagnostic tool RUT used in this study would serve as a better screening test. CagA and vacA s1 positive strains are the virulent ones in this locale. Usage of Clarithromycin and Amoxicillin can be continued as first line drugs in H.pylori eradication therapy in our population.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Helicobacter Pylori ; cagA gene ; VacA gene.
Subjects: MEDICAL > Microbiology
Depositing User: Punitha K
Date Deposited: 23 Jun 2017 07:10
Last Modified: 09 Dec 2018 03:56
URI: http://repository-tnmgrmu.ac.in/id/eprint/335

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