Hypopyon uveitis

Parvatha Sundari, N (2006) Hypopyon uveitis. Masters thesis, Madurai Medical College, Madurai.


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INTRODUCTION: Hypopyon: Hypopyon is a sterile collection of inflammatory cells in the inferior angle of the anterior chamber. Historical Background : Hypopyon was first considered to lie in the corneal substance and represented the gravitation of pus between the lamellae. It was called “onyx” so called from its resemblance to the root of a finger nail, an appearance which is now called hypopyon (under, pus). It was thus for a long time thought to be derived from the cornea, but the sterility of the material and the presence of pigmented granules in leucocytes demonstrated its origin from iris and ciliary body. Hypopyon Uveitis Hypopyon uveitis refers to certain specific uveitic entities that are characterized by a sterile collection of leucocytes & variable amounts of fibrin indicating a severe inflammatory process. Magnitude of the problem : The prevalence of uveitic entities that are likely to present with Hypopyon are in order of their prevalence. Idiopathic uveitis, Anky losing – spondylitis uveitis, other HLA B 27, uveitis (Reiter’s syndrome, Inflammatory bowel disease), Behcet’s disease, Herpes simplex keratouveitis, toxoplasmosis, toxocariasis, Histoplasmosis, ocular candidiasis, ocular syphilis, Traumatic iridocyclitis, leukemia, lymphoma (Maquerade syndrome). AIM OF THE STUDY: A prospective descriptive study was undertaken to study all the cases of uveitis (39 cases) with hypopyon that presented to the out patient department of Govt. Rajaji Hospital between June 2004 and August 2005 using a standard protocol and compared with the pattern of hypopyon uveitis in other studies. MATERIALS AND METHODS: 39 cases of uveitis with hypopyon were included in this prospective study conducted in our department between June 2004 and August 2005. INCLUSION CRITERIA: Any case of uveitis with significant anterior chamber inflammatory reaction and hypopyon without any primary ocular infection was included in the study. All the cases of endophthalmitis with hypopyon were included in the study except that caused by penetrating or perforating injuries of globe. EXCLUSION CRITERIA : Cases with infective corneal pathology or corneal trauma with hypopyon were excluded from the study thereby excluding exogenous infective aetiologies. SUMMARY OF RESULTS The results of the study are : HLA B 27 uveitis (28.2%) was the commonest cause of hypopyon uveitis in our study. Most cases of hypopyon uveitis were between 30-39 age group (18 cases) 46.15% 56.14% cases of hypopyon uveitis occurred in males and 43.58 % occurred in females. CONCLUSION: Hypopyon uveitis refers to certain specific uveitic entities that are characterized by a sterile collection of leukocytes and variable amount of fibrin indicating of severe inflammatory response. In the west the common cause of hypopyon uveitis are Behcet’s disease but in our subpopulation due to varied cultural, hygienic characteristics the aetiologies of hypopyon uveitis is expected to be different.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Hypopyon uveitis
Subjects: MEDICAL > Ophthalmology
Depositing User: Devi S
Date Deposited: 25 Sep 2017 09:54
Last Modified: 25 Sep 2017 09:54
URI: http://repository-tnmgrmu.ac.in/id/eprint/3326

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