Preparation and Usage of Pre-Gelatinized Starch for Enhancing the Solubility of Water Insoluble Anti-Inflammatory Agent

Aswathy, K S (2009) Preparation and Usage of Pre-Gelatinized Starch for Enhancing the Solubility of Water Insoluble Anti-Inflammatory Agent. Masters thesis, Sri Ramakrishna Institute of Paramedical Sciences, Coimbatore.

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Abstract

The present study aims at overcoming these problems by solid dispersion technology by using traditional carrier such as pregelatinized starch from their respective native starch of Potato, Tapioca and Maize. Pregelatinized starch is a modified starch that has been modified chemically or mechanically to rupture all or part of starch granules.4 The objective of the present study is to prepare pregelatinized starch from three sources such as Potato, Tapioca and Maize by a known method. It is a low cost carrier. Tapioca is cultivated in many regions of Tamil Nadu. It is very cheap so that we can reduce the cost of production significantly. The research work envisaged was: Literature survey on Solid dispersion methods and carriers used for solid dispersion, Preparation, Characterization and evaluation of solid dispersions of Etodolac with PGS prepared from Potato, Tapioca and Maize. Formulation and evaluation of Etodolac compressed tablets from selected Etodolac solid dispersion.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Pre-Gelatinized Starch; Water Insoluble; Anti-Inflammatory Agent
Subjects: PHARMACY > Pharmaceutics
Depositing User: Ravindran C
Date Deposited: 25 Sep 2017 05:55
Last Modified: 25 Sep 2017 05:55
URI: http://repository-tnmgrmu.ac.in/id/eprint/3275

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