Role of C Reactive Protein and Interleukin-6 in the Diagnosis of Neonatal Sepsis

Sankara Narayanan, P (2016) Role of C Reactive Protein and Interleukin-6 in the Diagnosis of Neonatal Sepsis. Masters thesis, Tirunelveli Medical College, Tirunelveli.


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Neonatal sepsis is a major cause of and mortalities in developing countries. Early diagnosis and treatment of the newborn infant with suspected sepsis are essential to prevent severe and life threatening complications. Early detection of bacterial sepsis is difficult for various reasons: firstly, early warning signs and symptoms are often nonspecific. Then there is the difficulty of distinguishing the clinical picture of neonatal sepsis from non-infectious causes. Further, microbiological culture results are not usually available until at least 48-72 hours after the specimen reaches the laboratory, and high false-negative rates of culture results may occur The findings of the present study confirm that the serum level of IL-6 is a more reliable marker than the serum levels of CRP. Serum level of IL-6 is also useful in evaluation of response of neonatal sepsis to antibiotic therapy.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Interleukin-6 ; C-Reactive Protein; Neonate ; Sepsis ; Antimicrobial Susceptibility.
Subjects: MEDICAL > Microbiology
Depositing User: Punitha K
Date Deposited: 23 Jun 2017 06:38
Last Modified: 25 Mar 2018 04:00

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