Clinico Pathological study of Small Round Cell Tumors in Pediatric Population

Priyathersini, N (2010) Clinico Pathological study of Small Round Cell Tumors in Pediatric Population. Masters thesis, Madras Medical College, Chennai.


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Malignancies Of Childhood Include A Well-Defined Spectrum Of Hematolymphoid Neoplasms, Organ Specific (Adrenal, Kidney, Liver) Neoplasms, Soft Tissues, Bone And Nervous System (Central And Peripheral) Neoplasms With Variable Biology. Small Round Cell Tumors (SRCT) Are A Subset Of Childhood Malignancies That Comprise A Group Of Diverse, Diagnostically Challenging Primitive Or Undifferentiated Neoplasms. These Tumors Have A Similar Histological Appearance That Is Small Round Blue Cells. They Share Many Morphological Similarities, However Their Unique Biological, Immunohistochemical, Ultrastructural And Genetic Characteristics Have Provided Substantial Insights Into The Pathology Of These Diverse Neoplasms. Traditionally Clinical Features And Light Microscopy With Aid Of Histochemistry And Ultrastructural Evaluation, Establish A Diagnosis. Additionally, Immunohistology, Cytogenitics And Molecular Studies Have Become Important In Diagnosis And In Defining Phenotype / Genotype, Patient Treatment Modalities And Prognosis In Specific Cases.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Clinico Pathological, Small Round Cell Tumors, Pediatric Population.
Subjects: MEDICAL > Pathology
Depositing User: Subramani R
Date Deposited: 23 Jun 2017 08:08
Last Modified: 13 Oct 2021 07:34

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