Parameswari, P (2013) Studies on Temperature Induced Mucoadhesive in Situ Gel Formulation of Rizatriptan Benzoate for Nasal Administration. Masters thesis, Adhiparasakthi College of Pharmacy, Melmaruvathur,Tamil Nadu, India.
|
Text
PARAMESWARI P.pdf Download (7MB) | Preview |
Abstract
Recently, controlled and sustained drug delivery has become the standard in modern harmaceutical design and an intensive research have been undertaken in achieving much better drug product effectiveness, reliability and safety. Over the past 30 years greater attention has been focused on development of controlled and sustained drug delivery systems. The studies revealed that, there were no much significant changes in percentage clarity, gelation temperature and gel melting temperature, pH, drug content and in-vitro drug permeation studies for three months at 40ºC. Out of the nine formulations, it appears that Formulation MG4 has the maximum potential in providing In situ gel nasal delivery system. This formulation was considered as best formulation for temperature induced nasal in situ gelling system for the treatment of anti-migraine activity with respect to its evaluation parameters like clarity, gelation temperature and gel melting temperature, pH, drug content and in-vitro drug release and this formulation may give patient friendly and needle free dosage form.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Temperature Induced; Mucoadhesive; Situ Gel Formulation; Rizatriptan Benzoate; Nasal Administration |
| Subjects: | PHARMACY > Pharmaceutics |
| Depositing User: | Ravindran C |
| Date Deposited: | 23 Jun 2017 05:00 |
| Last Modified: | 23 Jun 2017 06:08 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/298 |
Actions (login required)
 |
View Item |
