Preclinical and Clinical Study on Azhal Keel Vaayu (அழல் கீல் வாயு)

Suganya, G (2013) Preclinical and Clinical Study on Azhal Keel Vaayu (அழல் கீல் வாயு). Masters thesis, National Institute of Siddha, Chennai.

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Abstract

The present studies is to evaluate the Therapeutic efficacy of “Avuri Karpam”(Internal medicine) and “Vatha Noikku Ennai” (External medicine) in the Treatment of “Azhal Keel Vayu” (Osteoarthritis) for the reduction of pain, swelling and to improve the range of movements. Secondary objectives: To study the effectiveness of Varmam along with the efficacy of “Avuri Karpam” (Internal medicine) and “Vatha Noikku Ennai” (External medicine) in the Treatment of “Azhal Keel Vayu (Osteoarthritis)”. To study Azhal Keel Vayu, on the basis of Siddha principles like Envagai thervu, Mukkutram, Kaalam, Naadi, Neerkkuri, Neikkuri etc, in order to evaluate the pathology. To access the predominance of the disease related to age, sex, socio-economic status, habits, family history etc. To evaluate the safety of the trial drug by doing toxicological studies in animal models. To find out any side effect/adverse effect during the trial. The study results showed that 70 % had Good improvement, 22.5 % had Moderate improvement and 7.5 % had mild improvement. Varmam treatment along with the trial drugs showed good prognosis when compared to patients treated only with trial drugs. Hence the study reveals the importance of Varmam in treating Azhal keel vaayu. Clinically, no adverse effects were reported during the trial and the laboratory investigations were also within normal limits. So, the drug is assumed to be safe for humans. Acute toxicity study in animal models reveals that the trial drug “Avuri karpam” is safe. The safety of the trial drug was also proved from this study. Hence the study concludes that, the trial drugs are clinically effective in reduction of pain, swelling, restriction of movements. Because of the encouraging clinical results, it could be concluded that “Avuri karpam (Internally)” and “Vatha Noikku Ennai (Externally)” are effective in the treatment of “Azhal keel vaayu” (Osteoarthritis). However further work with large number of patients should be carried out towards finding the ideal dose response.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Avuri Karpam; Vatha Noikku Ennai; Azhal Keel Vayu; Varmam
Subjects: AYUSH > Sirappu Maruthuvam
Depositing User: Ravindran C
Date Deposited: 10 Aug 2017 06:43
Last Modified: 18 Apr 2018 01:31
URI: http://repository-tnmgrmu.ac.in/id/eprint/2623

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