Karthigeyan, T S (2015) Prediction of functional outcome in patients with spontaneous intracerebral hemorrhage using FUNC scoring. Masters thesis, Madras Medical College, Chennai.
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Abstract
Intracerebral hemorrhage (ICH) is the most fatal and disabling stroke subtype. Widely used tools for prediction of mortality are fundamentally limited in that they do not account for effects of withdrawal of care and are not designed to predict functional recovery. FUNC score was developed as an acute clinical score to predict likelihood of functional independence. Methods— In our study about 50 patients with ICH are selected. On admission complete neurological examination with CT Brain plain done , FUNC score made out . Patients were followed up for 90 days , FUNC score was compared with Glasgow Outcome Score at 90 days . Results— At 90 days, 38% patients achieved independence. Age, Glasgow Coma Scale, ICH location, volume , and pre-ICH cognitive impairment were independently associated with Glasgow Outcome Score > 4. The FUNC score was developed as a sum of individual points (0 –11) based on strength of association with outcome. The proportion of patients who achieved Glasgow Outcome Score > 4 increased steadily with FUNC score. No patient assigned a FUNC score > 4 achieved functional independence, whereas > 80% with a score of 11 did. The predictive accuracy of the FUNC score remained unchanged when restricted to ICH survivors only, consistent with absence of confounding by early withdrawal of care. Conclusions—FUNC score is a valid clinical assessment tool that identifies patients with ICH who will attain functional independence and thus, can provide guidance in clinical decision-making and patient selection for clinical trials.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Spontaneous; Intracerebral Hemorrhage; FUNC score |
| Subjects: | MEDICAL > General Medicine |
| Depositing User: | Punitha K |
| Date Deposited: | 04 Aug 2017 10:20 |
| Last Modified: | 09 Aug 2017 03:11 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/2496 |
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