Veena, Bheeman (2016) Correlation of Disease Severity, Estrogen, Progesterone & Epidermal Growth Factor Receptor Status with Altered Expression of Claudins 1, 3, 4 & 7, P53 & Ki67 Index in Carcinoma Breast. Masters thesis, ESIC Medical College & PGIMSR, Chennai.
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Abstract
Claudins [CLDN] are a new group of proteins that have of late attracted much attention as alterations in their expression is consistently associated with variations in outcomes in CA breast and many other malignancies. The results indicate that several associations and their implications have to be kept in mind while managing breast cancer and we can no longer stop with the standard protocols. Newer methods of prognostication are required. Promising drugs that target claudins are in clinical trials and they may improve the outcome drastically in these patients. Further studies will help clarify this information further
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Breast Cancer; Claudins; Claudin Low Breast Cancer; Triple Negative Breast Cancer; P 53; Ki 67; Estrogen Receptor; Progesterone Receptor; HER2neu molecular subtyping of breast cancer |
| Subjects: | MEDICAL > General Surgery |
| Depositing User: | Punitha K |
| Date Deposited: | 31 Jul 2017 11:51 |
| Last Modified: | 28 Sep 2017 03:15 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/2400 |
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