Comparison of biometric parameters in primary glaucomas and refractive errors.

Rajalakshmi, A R (2007) Comparison of biometric parameters in primary glaucomas and refractive errors. Masters thesis, Madras Medical College, Chennai.


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Glaucoma is a symptom complex wherein there is optic nerve head neuropathy with characteristic morphological and functional changes of the optic nerve, the major risk factor being increased intraocular pressure.” Glaucoma is a leading cause of irreversible blindness throughout the world. The World Health Organisation statistics published in 1995, indicate that Glaucoma accounts for blindness in 5.1 million persons or 13.5% of global blindness (behind cataracts and trachoma at 15.8 million and 5.9 million persons or 41.8 % and 15.5 % of global blindness, respectively) Although Glaucoma most commonly affects the elderly, it occurs in all segments of the society with significant health and economic consequences making it a major public health problem. Quigley has estimated that 66.8 million people are affected by primary Glaucoma worldwide, with 6.7 million people being bilaterally blind due to the disease. Aim of the study: To compare the ocular biometric values in primary open angle glaucomas with myopic and hypermetropic refractive errors. To analyse statistically the strength of association and predictability of the biometric parameters for the occurrence of primary angle closure glaucoma. Purpose of the study: Angle closure glaucoma is commoner in India than in the west, the reasons for which are not clearly understood. There is evidence in the literature that the eyes with angle closure glaucoma have a definite recognisable anatomical predisposition. Materials and methods: This is a prospective study done in Glaucoma Clinic - Regional Institute of Ophthalmology and Government Ophthalmic Hospital, Chennai between February 2005 and May 2006. A total of hundred patients were randomly selected. Informed consent was obtained from all the patients. The patients were divided into two groups of fifty each namely group A and group B. Group A - Primary Glaucoma Group & Group B - Refractive Error Group Conclusion: Primary angle closure glaucoma seems to be associated with shallower anterior chambers, thicker lenses and shorter axial length. The basic biometric parameters namely the anterior chamber depth, lens thickness, the axial length and the lens thickness / axial length ratio of the hypermetropes show a strong and significant association when compared with the Primary angle closure glaucoma patients. Lens thickness / axial length factor standardizes the assessment of the eyes with angle closure glaucoma. It is highly reliable and reproducible and easily chart the clinical course of the eye examined. As ultrasonography is now a commonly done office procedure, measurements of axial length, lens thickness, and the anterior chamber depth could be done routinely as part of screening to predict the eyes that may go in for angle closure glaucoma.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Primary glaucoma; refractive errors; comparison; biometric parameters
Subjects: MEDICAL > Ophthalmology
Depositing User: Devi S
Date Deposited: 28 Jul 2017 05:54
Last Modified: 28 Jul 2017 05:54

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