Study of Drug Prescription Pattern of Anti-Hypertensives in a Tertiary Care Hospital

Sivakumar, A (2014) Study of Drug Prescription Pattern of Anti-Hypertensives in a Tertiary Care Hospital. Masters thesis, J K K Nataraja College of Pharmacy, Komarapalayam.

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Abstract

Hypertension is a common disease that is defined simply as persistently elevated arterial blood pressure (BP). Increasing awareness and diagnosis of hypertension and improving control of BP with appropriate treatment are considered critical Public health initiatives to reduce cardiovascular morbidity and mortality. It is a heterogeneous medical condition. In most patients it results from unknown pathophysiologic etiology (essential or primary hypertension). While this form of hypertension cannot be cured, it can be controlled. A small percentage of patients have a specific cause of their hypertension (secondary hypertension). It is defined simply as persistently elevated arterial BP. The JNC7 classification of BP in adults (age > 18 years) is based on the average of two or more properly measured BP readings from two or more clinical encounters2. It includes four categories, with normal values considered to be a systolic blood pressure (SBP) of less than 120 mm Hg and a diastolic blood pressure (DBP) of less than 80mmHg. Prehypertension is not considered a disease category but identifies patients whose BP is likely to increase into the classification of hypertension in the future. There are two stages of hypertension, and all patients in these categories need drug therapy.initiatives to reduce cardiovascular morbidity and mortality. It is a heterogeneous medical condition. In most patients it results from unknown pathophysiologic etiology (essential or primary hypertension). While this form of hypertension cannot be cured, it can be controlled. A small percentage of patients have a specific cause of their hypertension (secondary hypertension). It is defined simply as persistently elevated arterial BP. The JNC7 classification of BP in adults (age > 18 years) is based on the average of two or more properly measured BP readings from two or more clinical encounters2. It includes four categories, with normal values considered to be a systolic blood pressure (SBP) of less than 120 mm Hg and a diastolic blood pressure (DBP) of less than 80mmHg. Prehypertension is not considered a disease category but identifies patients whose BP is likely to increase into the classification of hypertension in the future. There are two stages of hypertension, and all patients in these categories need drug therapy.Aim of the study was to evaluate the utilization of antihypertensive drugs in hypertensive patients.ARBs are the most used antihypertensive agent especially Telmisartan.ACEIs are the least prescribed antihypertensive agent.Double and triple combination therapies are more used when compared to monotherepy.In combination therapy ARB and Diuretics (16.23%) are placing the first place in prescription and followed by ARB and CCB (12.73%). The least combination was BB with Diuretics (1.93%).

Item Type: Thesis (Masters)
Uncontrolled Keywords: Drug Prescription Pattern ; Anti-Hypertensives ; Tertiary Care Hospital.
Subjects: PHARMACY > Pharmacy Practice
Depositing User: Ravindran C
Date Deposited: 28 Jul 2017 05:49
Last Modified: 18 Dec 2017 05:33
URI: http://repository-tnmgrmu.ac.in/id/eprint/2316

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