Prema, S (2012) A clinical study on retinal vasculitis. Masters thesis, Madras Medical College, Chennai.
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Abstract
Retinal vasculitis is considered to be Type 3 hypersensitivity reaction of retinal vasculature affecting veins, arteries or both. The pathological evidence indicates that the basic pathology is perivascular. The disease is characterized by occurrence of hemorrhages in the retina, vitreous, or with recurrence of haemorrhages. The disease can progress and lead to fibovascular membrane and tractional retinal detachment, complicated cataract and secondary glaucoma. The first attempt to discuss in detail the clinical syndrome of recurrent haemorhages was made by HENRY EALES (1880-82).1 PERLS(1873) and ANGELUCCI(1878) studied the histological appearance of periphlebitis. WADSWORTH (1887) was the first to describe the clinical picture of perivasculitis. AXENFELD and STOCK (1909-11) drew attention to the etiological significance of tuberculosis. Primary vasculitis is predominant (50%)among the vasculitis in our study. From our intervention it was clear that steroid in any mode of administration was efficacious in controlling the inflammation in acute disease . 2 patients (16.67%) in the oral steroid group and 1 patient (8.33%) in posterior sub-tenon group required immunosuppressants. No patients in our study required laser theraphy for neovascularisation during the follow up period. The final visual outcome in Subgroup 1(ORAL STEROIDS) at end of 16 weeks was 6/6 in 83.33%,16.67% had visual acuity of 6/12-6/18 Subgroup 2(POSTERIOR SUB-TENON) at the end of 8 weeks was 6/6 in 91.67%, 8.33% had visual acuity of 6/12-6/18. No activity(grade-0 vitritis) was seen in 83.33% of cases in the subgroup 1 and 91.67% of subgroup 2. Male predliction was noted in our study. 30-40yrs is the predominant age group affected in our study Bilaterality was predominant among patient with Eales disease and vasculitis due to Systemic disease. In patients with Primary vasculitis local steroid administered with safety and skill is efficacious in controlling active disease with minimal complication compared to systemic administration. Although systemic steroids are equally efficacious in controlling active disease and easily administered, adverse systemic complications is a matter of concern.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | retinal vasculitis; |
| Subjects: | MEDICAL > Ophthalmology |
| Depositing User: | Devi S |
| Date Deposited: | 27 Jul 2017 09:31 |
| Last Modified: | 27 Jul 2017 09:31 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/2268 |
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