Ashok Kumar, Bathini (2012) Method Development and Validation of Stability Indicating Rphplc Method for Simultaneous Estimation of Levofloxacin and Azithromycin in Pharmaceutical Tablet Dosage Form. Masters thesis, R V S College of Pharmaceutical Sciences, Coimbatore.
|
Text
Ashok Kumar Bathini.pdf Download (2MB) | Preview |
Abstract
Analytical Chemistry is defined as the “science and the art of determining the composition of materials in terms of the elements or compounds contained”. This branch of chemistry,which is both theoretical, and a practical science, is practiced in a large number of laboratories in many diverse ways while analytical method, is a specific application of a technique to solve an analytical problem. Methods of analysis are routinely developed, improved and validated.collaboratively studied and applied. In analytical chemistry it is of prime importance to gain information about the qualitative and quantitative composition of substances and chemical species, that is, to find out what a substance is composed and exactly how much. In quantitative analysis the question is how much is present? The research work in this thesis is based on this criterion. The Present study method for determination of Levofloxacin and Azithromycin by RP-HPLC mehod are reliable, accurate, and precise. The values of standard deviation were found satisfactory and the recovery studies were close to 100%. The method does not require prior separation of one drug from other. System suitable parameters, precision, linearity, accuracy, precision,Robustness and stability according to ICH guidelines were found to be satisfactory.The proposed method was simple, specific, requires short time to analyse samples andeasy to perform.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Validation; Stability; Rphplc Method; Simultaneous; Levofloxacin; Azithromycin; Pharmaceutical Tablet Dosage |
| Subjects: | PHARMACY > Pharmaceutical Analysis |
| Depositing User: | Ravindran C |
| Date Deposited: | 27 Jul 2017 07:02 |
| Last Modified: | 06 Oct 2017 03:35 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/2240 |
Actions (login required)
 |
View Item |
