Basal Cell Carcinoma: A Prospective clinico epidemiological & pathological study

Ammasaigoundan, V (2016) Basal Cell Carcinoma: A Prospective clinico epidemiological & pathological study. Masters thesis, Madras Medical College, Chennai.


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To find out the age and sex incidence of basal cell carcinoma in patients attending the outpatient department of dermatology, RGGGH, Chennai. To find out the various clinical and histopathological features of basal cell carcinoma. MATERIALS AND METHODS: This was a prospective observational study carried out at dermatology outpatient department, RGGGH, Chennai. Patients with clinical diagnosis of basal cell carcinoma were included in the study after thorough history, clinical examination, routine and special investigations like skin biopsy. RESULTS: Out of 20 patients with basal cell carcinoma 6 were males and 14 were females with a male to female ratio of 1:2.33. Females (70%) were most commonly affected than males (30%). Most commonly affected age group was 50 – 70 years (70%). Distribution of basal cell carcinoma in our study was confined to head and neck area and the most common site involvement was nose (30%), followed by periocular region (25%) and cheek (15%). Most common morphological subtype encountered in our study was nodular / noduloulcerative BCC (70%), followed by pigmented type (25%) and superficial BCC (5%). The most common histological variant observed in our study was nodular type (55%), followed by pigmented variant (25%), adenoid (5%), basisquamous (5%), superficial BCC (5%) and BCC with sebaceous differentiation (5%). CONCLUSION:This study highlights a paradoxically increasing trend of BCC with female predilection.  Since early age of onset of basal cell carcinoma being reported in persons with genetic defect, these patients should be advised for periodic followup and strict photo protective measures. Early detection and treatment of lesions are crucial to decrease the functional and cosmetic morbidity, this study highlights the importance of improving awareness among general practitioners, public health workers and general population.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Basal Cell Carcinoma ; Clinical Variants ; Exicision Biopsy ; Histopathology.
Subjects: MEDICAL > Dermatology Venereology and Leprosy
Depositing User: Punitha K
Date Deposited: 26 Jul 2017 09:19
Last Modified: 01 Mar 2018 02:15

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