Jayakumar, N (2016) Audiologic monitoring and renal function monitoring for DR-TB patients under PMDT for six to nine months period in Tirunelveli Medical College Hospital DR-TB Unit. Masters thesis, Tirunelveli Medical College, Tirunelveli.
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Abstract
Audiologic monitoring and renal function monitoring for Drug Resistant patients under programmatic management of drug resistant tuberculosis reatment for six to nine months period in Tirunelveli Medical College Hospital DR-TB UNIT, from January 2014 to December 2014. MATERIALS AND METHODS: Total of 152 newly diagnosed DR-TB patients those registered in DR-TB centre , Tirunelveli medical college hospital from January 2014 to December 2014 were screened. INCLUSION CRITERIA: All newly diagnosed (n- 51) DR-TB patients with normal baseline audiometry and normal serum urea and creatinine levels were included in this study RESULTS: 1. In this prospective observational study, during the intensive phase of CATEGORY IV regimen 43.3% patients developed statistically significant OTOTOXICITY , 2% patients developed NEPHROTOXICITY and 2% of patients developed BOTH OTOTOXICITY AND NEPHROTOXICITY. 2. OTOTOXICITY- 63.63% patients developed bilateral hearing loss and 36.36% patients developed unilateral hearing loss. among the patients with ototoxicity 75% patients had mild hearing loss, and mostly during first three months period of the intensive phase. 3. In our study 64% patients with hearing loss are asymptomatic and 36% patients noticed symptoms associated with hearing loss. CONCLUSION: In our study 64 % of asymptomatic hearing loss cases were picked up by using pure tone audiometry. Early detection of the hearing loss among these patients shall improve adherence to the treatment.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Audiologic monitoring ; renal function monitoring ; Drug Resistant Tuberculosis patients ; Extensively Drug Resistant Tuberculosis. |
| Subjects: | MEDICAL > Tuberculosis and Respiratory Medicine |
| Depositing User: | Punitha K |
| Date Deposited: | 25 Jul 2017 12:06 |
| Last Modified: | 08 Nov 2018 07:41 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/2174 |
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