Nandagopan, S (2013) Comparison of hemodynamic effects of lignocaine 2% with adrenaline in two different concentrations of 1:80,000 and 1:2,00,000. Masters thesis, Sree Mookambika Institute of Dental & Medical Sciences, Kulasekharam.
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Abstract
Aims & Objectives: The present study was designed to compare the hemodynamic parameters during administration of local anesthetics agent lignocaine 2% without adrenaline and with adrenaline in different concentrations such as 1:80,000 and 1:2, 00,000 in minor oral surgical procedures with regard to systolic blood pressure, diastolic blood pressure, heart rate and oxygen saturation Materials and Methods: Thirty ASA grade I patients were selected who were to undergo multiple minor oral surgical procedures. All patients received 1.8 ml of local anesthetic solutions during each appointment. All patients were categorized into groups based on the choice of local anesthetic agent used with there respective concentration of adrenaline. The total no. of groups being three, group I included patients who received plain Lignocaine 2%, group II received Lignocaine 2% with adrenaline 1:80,000 and group III received Lignocaine 2% with adrenaline 1:2, 00,000. Under each group, the following parameters such as oxygen saturation, heart rate, systolic and diastolic blood pressure were recorded immediately after administration and at timely intervals of 5 min, 10 min, 15 min, 20 min and 30 min. Results: It was noticed that oxygen saturation did not show any variations while using lignocaine 2% or lignocaine 2% with adrenaline 1:80,000 or lignocaine 2% with adrenaline 1: 2,00,000. Those patients who received plain lignocaine 2% showed only minor variations in HR which was not significant while those patients who received lignocaine 2% with adrenaline 1:80,000 and lignocaine 2% with adrenaline 1:2,00,000 showed an increase in heart rate after administration of local anesthetic. Patients receiving local anesthetic with adrenaline in concentrations of 1:80,000 and 1:2,00,000 showed a bimodal change in systolic blood pressure. An initial decrease in systolic blood pressure was noted immediately after administration and then increases at 10 min following administration. Again after 10 min period, systolic pressure decreased gradually till 30 min. Diastolic blood pressure did not show any variations in those patients who received plain lignocaine 2% but was noted to be decreasing in patients receiving local anesthesia with adrenaline in concentrations of 1:80,000 and 1:2,00,000. Conclusion: To conclude, even though use of lignocaine with adrenaline is associated with changes in blood pressure and heart rate, clinically they are less significant and such changes did not produce any marked systemic untoward outcome at any of the studied adrenaline concentrations of 1:80,000 or 1:2,00,000.
| Item Type: | Thesis (Masters) |
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| Uncontrolled Keywords: | Hemodynamic effects ; lignocaine ; adrenaline. |
| Subjects: | DENTAL > Oral and Maxillofacial Surgery |
| Depositing User: | Thavamani K |
| Date Deposited: | 18 Aug 2017 11:17 |
| Last Modified: | 13 Nov 2017 15:51 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/2166 |
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