Nithya Kumar, S (2023) A Clinical study of Role of Papaya (Carica Papaya) Dressing in the Management of Diabetic Ulcer in RGGGH. Masters thesis, Madras Medical College, Chennai.
Full text not available from this repository.Abstract
INTRODUCTION: The incidence of diabetes mellitus (DM) is assuming epidemic proportions in the world, particularly in India. Lower extremity disease, including peripheral neuropathy, foot ulceration, peripheral arterial disease and lower extremity amputation, is twice as common in diabetic persons compared to non-diabetic persons. It affects 30 per cent of diabetic persons who are older than 40 yrs. In persons with diabetes mellitus, the annual population-based incidence of foot ulcer ranges from 1.0% to 4.1% and the prevalence ranges from 4% to 10%. This suggests that the lifetime incidence of diabetic foot ulcer may be as high as 25%. Plantar ulceration often leads to amputation. Diabetic foot ulcer precedes almost 85% of amputation. Diabetic foot ulcer is characterised by a classical triad of neuropathy, ischemia, and infection. Due to the metabolic mechanisms in DM, there is an increased risk of infections and poor wound healing due to a series of mechanisms which include decreased cell and growth factor response, diminished peripheral blood flow and decreased local angiogenesis. Thus the feet is predisposed to peripheral vascular disease, damage of peripheral nerves, deformities and gangrene. Loss of sensation due to peripheral neuropathy may result in painless injuries. AIMS AND OBJECTIVES: 1. To study efficacy of papaya dressing. 2. Number of days needed for healing. 3. Rate of reduction in mean surface area. 4. To assess the effect of papaya on bacterial load by comparing culture sensitivity of wound before and after application. MATERIAL AND METHODS: Study Centre: Institute of General surgery, Madras Medical College, Rajiv Gandhi Government General Hospital, Chennai 600 003. Duration of study: 6 months (July 2022 to December 2022). Sample size: 60 patients. Study Design: Prospective study. Methodology: Prospective longitudinal study performed at RGGGH, where 60 patients with diabetic foot ulcer more than 2 weeks participated in the present study. The wounds covered with the raw papaya slices were applied to the wounds over sterilized gauze pieces for dressing. Patients and attendants were also educated for the dressing. Dressings were changed after every 24 hours. Patients were discharged after initial wound management, pus culture sensitivity and control of blood sugar. after 1 week the wounds were examined for healthy granulation tissue and reduction in surface area, culture reports. Inclusion criteria: • Patients between 12 to 75 years of age. • Duration of the diabetic ulcer more than 2 weeks. • Size of ulcer less than 15 x 15 cm. • Patients giving consent for papaya dressing. Exclusion criteria: • Pulse less limb. • Immunocompromised patients. • Associated septicaemia and osteomyelitis. • Skin malignancies. • Diabetic Ketoacidosis. • Exposed bones, tendon. • Charcot joint. CONCLUSION: Papaya (CARICA PAPAYA) Dressing in the management of Diabetic ulcer shows cost effective, with favourable outcomes in terms of duration of healing, less surgical debridement and enzymatic sloughectomy
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 220120100510 |
| Uncontrolled Keywords: | Papaya, Carica Papaya, Dressing, Management, Diabetic Ulcer, RGGGH. |
| Subjects: | MEDICAL > General Surgery > MEDICAL > General Surgery |
| Depositing User: | Subramani R |
| Date Deposited: | 15 Jan 2024 06:31 |
| Last Modified: | 19 Jan 2024 16:32 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/21300 |
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