Prabhakaran, D (2022) Clinical Evaluation of the Effect of Mandoora Adai Kiyazham for the treatment of Vatha Soobai. Masters thesis, Government Siddha Medical College, Palayamkottai.
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Abstract
The disease vatha soobai was taken for the clinical study with Mandoora adai kiyazham as Oral route. For the clinical study, 40 children were selected based on the approved protocol. This study has been approved By GSMC/IEC-VII/2020-Br.iv/15-06.11.2020. Animal studies were carried out after obtaining approval from the Instituitional Animal Ethical Committee (IAEC) Approved and its number SARPC/IAEC/26/2021 and the trial was registered in Clinical Trial Registry of India CTRI/2020/12/030071. Hence the study is safely executed on children and there was no adverse drug reactions noted during the study period. • 40 children were treated with trial medicine in OPD, IPD of Department of Kuzhanthai Maruthuvam. • Before, treatment, the signs and symptoms for vatha soobai are noticed and confirmed by lab investigation. Findings revealed about the impact of the disease in the body. During treatment, the dose of 15 -30 ml of Mandoora adai kiyazham, twice a day after meals, has been given to children affected by vatha soobai depending on their age, body weight and severity of the disease. • No adverse effects were reported during or after the course of treatment. The drug selected for the study was found to be easily available drug, easy to administrate and also more effective against vatha soobai without any adverse effects. CONCLUSION: In the study, the patients were selected based on Inclusion and Exclusion criteria. It is clear that Vatha soobai is caused due to derangement of pitham followed by derangement of vatham and kabham. • The trial drug Mandoora Adai Kiyazham is easily available and cost effective taken 30 days for study. It increases in the Hemoglobin, total RBC count, PCV, MCV, MCH, MCHC when given regularly along with other healthy supplementary diets. Symptomatically Puffiness of face, Pedal oedema relieves within 2 week and the children were improved with good appetite. • Hematological studies and in vitro studies of Mandoora Adai Kiyazham clearly Shows the drug act as Diuretic action in dose dependent manner. • The pre-clinical studies done for the trial drug had been proved effective for Vatha soobai and the study proved that the trial drug has given 85% good results in my clinical trial. • Hence, the study concluded that the Mandoora Adai Kiyzham along as internal medicines treats Vatha Soobai along with healthy diet. • No adverse effects were noted the entire course of treatment.
| Item Type: | Thesis (Masters) |
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| Additional Information: | Reg.No.321914005 |
| Uncontrolled Keywords: | Clinical Evaluation, Mandoora Adai Kiyazham, treatment, Vatha Soobai. |
| Subjects: | AYUSH > Kuzhanthai Maruthuvam |
| Depositing User: | Subramani R |
| Date Deposited: | 01 May 2023 15:26 |
| Last Modified: | 14 Feb 2024 15:58 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/21176 |
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