Standardization and Pharmacological screening of Hepatoprotective, Diuretic, and Anti-Oxidant activities of siddha formulation Milagu Usitham

Velaman, D (2022) Standardization and Pharmacological screening of Hepatoprotective, Diuretic, and Anti-Oxidant activities of siddha formulation Milagu Usitham. Masters thesis, National Institute of Siddha, Chennai.

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Abstract

The test drug Milagu Usitham was selected from the Siddha literature Anuboga vaidya navaneetham to Standardize and pharmacological screening of hepatoprotective, diuretic and anti oxidant activities. ❖ All the ingredients were identified and authenticated by the experts and were purified and the medicine was prepared as mentioned in the Siddha literature. ❖ Reviews of literature in various categories were carried out. Siddha aspect, modern aspect and pharmacological aspect were disclosed about the ingredients of the drug Milagu Usitham. ❖ The drug was subjected to qualitative analysis such as physicochemical, chemical analysis, Instrumental and pharmacological analysis which provided the key ingredients present in the drug thus it accounts the efficacy of the drug. ❖ Pharmacological studies revealed that the drug milagu usitham exhibited significant hepatoprotective, Diuretic activity in animal models and anti oxidant in Invitro model. ❖ Results and discussion gives the necessary justifications to prove the potency of the drug Milagu Usitham. ❖ Conclusion gives a compiled form of the study and explains the synergistic effect of all the key ingredients and activities that supports the study. CONCLUSION: Milagu Usitham a traditional Siddha formulation was prepared as per the procedures mentioned in Siddha literature. From the literature evidence, Physico Chemical analysis, Chemical analysis, Instrumental analysis and Pharmacological studies, the author concludes that the drug MilaguUusitham is safe and it has significant effect of Hepatoprotective, Diuretic and Anti-oxidant activities. It was concluded that the Milagu Usitham proved that it has remarkable medicinal value against the diseases of liver which is cost effective and easy to prepare. So this must be implicated in the future for clinical studies.

Item Type: Thesis (Masters)
Additional Information: Reg.No.321912208
Uncontrolled Keywords: Standardization and Pharmacological screening, Hepatoprotective, Diuretic, and Anti-Oxidant activities, siddha formulation, Milagu Usitham.
Subjects: AYUSH > Gunapadam
Depositing User: Subramani R
Date Deposited: 01 May 2023 14:44
Last Modified: 14 Feb 2024 15:28
URI: http://repository-tnmgrmu.ac.in/id/eprint/21171

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