Kanitha Deepika, S (2021) Pharmaceutical Characterization of Topical Erythromycin Nanoemul Gel for Acne Vulgaris. Masters thesis, Swamy Vivekanandha College of Pharmacy, Tiruchengodu.
Full text not available from this repository.Abstract
The main objective of the investigation is to formulate nanoemulsion in gel formulation of Erythromycin in order to overcome the drawbacks associated with the other dosage forms and in order to improve the overall efficacy of the drug. The present work aimed to develop nanoemulsion of mefenamic acid for improving its efficacy, stability, and permeability for the treatment of Acne Vulgaris. The aim of this work was to develop an emulgel formulation of Erythromycin, a hydrophobic drug, using Carbopol934 as gelling agent and Olive oil, penetration enhancer. The influence of gelling agent and penetration enhancers was investigated. The rheological studies, In vitro release, stability studies, thermodynamic stability studies of the prepared Nanoemulgels were also evaluated. The prepared nanoemulsions were placed in tightly closed glass vials and stored at ambient temperature. These drug-loaded formulations were subjected to accelerated, thermodynamic stability studies like centrifugation stress, heating cooling stress and freeze-thawing stress, appearance, percent transmittance, refractive index, Electrical conductivity. In conclusion, nanoemulsion of Erythromycin was developed to a satisfactory level in terms of physical stability tests, appearance, refractive index, Electrical conductivity, lower surfactant concentration. The present study endorsed nanoemulsion of Erythromycin to be a promising choice over conventional formulations for the treatment of Acne Vulgaris.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 261910602 |
| Uncontrolled Keywords: | Pharmaceutical Characterization, Topical Erythromycin Nanoemul Gel, Acne Vulgaris. |
| Subjects: | PHARMACY > Pharmaceutics |
| Depositing User: | Ramakrishnan J |
| Date Deposited: | 12 Aug 2022 08:42 |
| Last Modified: | 12 Aug 2022 08:42 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/20736 |
Actions (login required)
 |
View Item |
