A Study of Side Effects & Tolerability of Intravesical ‘BCG’ in Superficial Bladder Cancer.

Sumit, Goyal (2008) A Study of Side Effects & Tolerability of Intravesical ‘BCG’ in Superficial Bladder Cancer. Masters thesis, Cancer Institute (WIA), Chennai.


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INTRODUCTION: The Ca Bladder is one of the important tumors of the genitourinary cancers and usually Affects the people all around the globe. Broadly urinary bladder cancers can be divided into Superficial, muscle invasive and metastatic cancers. Of which superficial cancers constitute the Majority of cases. Superficial bladder cancers are the tumors confined to the mucosa and Submucosa (Ta, Tis & T1). This is a heterogeneous disease with variable natural history. At one end of the spectrum are low grade tumors (Ta) with low potential for progression & rarely represent a threat to the patient, while at the other end are the high grade (T1) tumors With high malignant potential with significant progression and death. Although thorough endoscopic tumor resection remains the principal treatment, Intravesical agents have become an important in the subgroup of tumors that are at risk of Progression. Intravesical Bacillus Calmette-Guerin, is effective treatment in preventing Recurrences & delaying progression in superficial bladder cancer. It has been in use since the 1980's, and is the most proven and effective form of immunotherapy. Though therapy with BCG is generally safe, it is not completely, without side effects. This study was done to know the various side effects, outcomes and tolerability of the Therapy. AIMS AND OBJECTIVES: 1. To study the side effects & complications following intravesical instillation of BCG. 2. To study the tolerability following administration of intravesical BCG.

Item Type: Thesis (Masters)
Uncontrolled Keywords: Side Effects ; Tolerability ; Intravesical ; ‘BCG’ ; Superficial Bladder Cancer.
Subjects: MEDICAL > Medical Oncology
Depositing User: Subramani R
Date Deposited: 19 Aug 2017 03:44
Last Modified: 19 Aug 2017 03:44
URI: http://repository-tnmgrmu.ac.in/id/eprint/2045

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