R N Madhurima, (2023) A Prospective Study of Epidemiological, Clinical, Toxicity, Outcome of Patients Admitted with History of Acute Drug Poisoning in a Tertiary Care Centre. Masters thesis, Madras Medical College, Chennai.
|
Text
2001 001 23 R N Madhurima.pdf Download (1MB) | Preview |
Abstract
BACKGROUND: The patients with acute drug poisoning are relatively common in hospitals, usually require relatively simple care and have good short-term outcome. However, some of these patients are at risk of acute morbidity and poor long-term outcome. In most cases the needed care is symptomatic, the hospital length of stays are less than 3 days and primary outcome is good. The substances used in self poisoning vary depending on area and the culture. Typical agents used in self poisoning include pharmaceutical products, mostly psychoactive drugs and paracetamol, pesticides, rodenticides, household chemicals, and illegal drugs. Alcohol intake is often associated with self poisonings. Patients admitted to hospital due to acute self induced drug poisoning present various types of Motivation. Some poisoning accidental, mostly among children or accidents in recreational use and in self medication. Patients admitted to hospital due to hospital often have previous admissions due to self poisoning. OBJECTIVES: 1. To know the epidemiological profile of patients admitted in our hospital with history of Acute tablet poisoning. 2. To study the various clinical presentations, haematological and biochemical, radiological abnormalities associated with the outcome of the patient MATERIALS AND METHODS: After selecting patients as per inclusion and exclusion criteria, detailed history regarding type of drug intake quantity of consumption time of consumption, intent suicidal or accidental,demographic data and clinical presentations. Blood investigations like complete blood picture,renal function tests, liver function tests, serum electrolytes, coagulation profile, chest X-ray, ecg, ABG, urine analysis, toxic drug analysis and their reports were included in this study. Outcome of the various drug poisonings were recorded. RESULTS: In the present study 80 patients admitted and studied over a period of 6 months. Majority of participants were between 31-40 yrs. Majority of patients were from lower middle class and studied Above high school. Among the total study participants, BENZODIAZEPINES are the most common drug poisoning followed by Non steroidal anti inflammatory drugs and anti hypertensives. Mean duration of stay in hospital of study participants was 4-7 days. All the study participants were recovercd and discharged. CONCLUSION: Patients hospitalised with acute drug poisoning have relatively good short term outcomes. In the long term however, these patients have a high rate of re admissions due to drug poisoning Most of the adolescents hospitalised due to acute self poisoning were likely to be depressive and had repeated self harm. There is significant association noted between time since consumption, comorbidities, class of drug taken, specific antidote and organ failure.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | Reg.No.200120100525 |
| Uncontrolled Keywords: | Epidemiological, Clinical, Toxicity, Outcome, Acute Drug Poisoning, Tertiary Care Centre. |
| Subjects: | MEDICAL > General Medicine > MEDICAL > General Medicine |
| Depositing User: | Thavamani K |
| Date Deposited: | 26 May 2022 05:48 |
| Last Modified: | 17 Mar 2024 15:29 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/20206 |
Actions (login required)
 |
View Item |
