A Study to Assess the Utility of Peradeniya Organophosphorus Poisoning (POP) Scale, Poisoning Severity Score (PSS) and Glasgow Coma Scale (GCS) in Predicting Severity and Treatment Outcome in Acute Organophosphorus Poisoning Patients Admitted in a Tertiary Care Centre

Annadurai, S (2023) A Study to Assess the Utility of Peradeniya Organophosphorus Poisoning (POP) Scale, Poisoning Severity Score (PSS) and Glasgow Coma Scale (GCS) in Predicting Severity and Treatment Outcome in Acute Organophosphorus Poisoning Patients Admitted in a Tertiary Care Centre. Masters thesis, Madras Medical College, Chennai.

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Abstract

INTRODUCTION: Organophosphate compounds are often used for homicidal and suicidal Purposes and continues to be an important cause of poisoning in developing countries including India. lt accounts for about 80% of pesticide related hospital admissions. In rural areas hospitals are not adequately staffed or equipped to treat very sick patients. ICU and ventilators are in short supply to meet the above burden. In such situations early assessment by clinical markers is very important to categorise the severity and early referral to higher centres so that aggressive treatment can be initiated immediately. AIMS AND OBJECTIVES: Study aimed to assess the severity of OP poisoning by POP scale, PSSS and GCS and to compare POP scale, PSS and GCS in predicting the treatment outcome in OPC poisoning. MATERIAL AND METHODS: In our study, 142 patients who satisfied the inclusion and exclusion Criteria with Organophosphorus compound poisoning were included. POP score, PSS and GCS were assessed at the time of presentation and were grouped based on the severity. These scores were evaluated individually in predicting the need Ventilator requirement and mortality in OPC poisoning and the scores were compared with each other. So as to assess which score was better in predicting the severity of OPC poisoning. RESULTS: Ventilator requirement and mortality was found to be in 37.3% and 8.5% of the patients respectively. Intubation and mortality rates were higher in patients with a severe category of POP score, PSS and GCS with a significant p value of (0.005), than in the mild to moderate category. All three scores correlated well in predicting the requirement of mechanical ventilation and mortality in OPC poisoning cases. CONCLUSION: All the three scoring systems are simple and effective tools that can be assessed based on the clinical examination. For resource limited countries, like India, any of the three scoring systems can be used at the primary health care setting level which helps in making timely decisions regarding need for mechanical ventilation and timely shifting of patients to the ICU care setting for management.

Item Type: Thesis (Masters)
Additional Information: 200120100505
Uncontrolled Keywords: Utility, Peradeniya Organophosphorus Poisoning (POP) Scale, Poisoning Severity Score (PSS), Glasgow Coma Scale (GCS), Predicting Severity, Treatment Outcome, Acute Organophosphorus Poisoning Patients, Tertiary Care Centre.
Subjects: MEDICAL > General Medicine
> MEDICAL > General Medicine
Depositing User: Thavamani K
Date Deposited: 24 May 2022 00:41
Last Modified: 16 Mar 2024 06:39
URI: http://repository-tnmgrmu.ac.in/id/eprint/20114

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