Vigneshwar, M (2019) Formulation and Evaluation of Quercetin crowned N-acetylcysteine liposomes. Masters thesis, Jaya College of Paramedical Sciences, Thiruninravur, Chennai.
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Abstract
The formulation and evaluation of the prepared Quercetin crowned N-acetyl Cysteine liposomes shows that there is no incongruity between drug and other ingredients used in the preparation of the formulation. The study also the reverse phase evaporation method is very suitable for liposomal formulation which is more effective in our study compared to the literature. The evaluation shows that the formed liposomes are unilamellar structures. The entrapment and loading of the drug was better in the method compared to the previous study. The AST results also suggested that the formulation is highly stable. The evaluation studies clearly prove that the formed liposomes are well formulated with crowned by Quercetin on the N-acetylcysteine liposome. Further the study has to be conducted for in-vivo studies to find the bioavailability, pharmacokinetic, Drug interactions (if any) and its therapeutic efficacy. CONCLUSION The formulation shows a newer alternative option in the novel drug delivery combined with the bioenhancing technique which will more effective then the single technique of either bioenhancing or novel formulation This type of techniques will be very useful for low bioavailable drugs which are having larger dose for their therapeutic effect and it also proves to be a very dose effective in terms of N-acetylcysteine.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 261711357 |
| Uncontrolled Keywords: | Formulation, Evaluation, Quercetin crowned N-acetylcysteine liposomes |
| Subjects: | PHARMACY > Pharmaceutics |
| Depositing User: | Ramakrishnan J |
| Date Deposited: | 16 May 2022 07:06 |
| Last Modified: | 16 May 2022 07:06 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/20039 |
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