Suthish, S (2019) Formulation and In-Vitro Evaluation of Ethosomel Gel of Tolnaftate. Masters thesis, PGP College of Pharmaceutical Science and Research Institute, Namakkal.
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Abstract
The current study is so designed to bypass the GI so as to deliver the drug through skin by attaining greater penetration and longer resident time so as to enhance bioavailability using ethosomes as the nanocarriers (novel drug delivery systems).The main objective of the current study was to develop and evaluate an ethosomal topical gel using Terbinafine hydrochloride as the antifungal agent (novel vesicular drug delivery system).To develop Nano ethosomal formulation using Terbinafine hydrochloride, phospholipids along with ethanol for effective therapy against fungal infections such as ringworm, athlete's foot(tinea pedis), and jock itch (tinea cruris). To formulate Ethosomes those are able to improve skin delivery of drugs both under occlusive and non‐occlusive conditions. To assess and evaluate ethosomal as well as gel characteristics. To develop effective, cost efficient and safe formulation against onchomycosos.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 261711453 |
| Uncontrolled Keywords: | Formulation, In-Vitro Evaluation, Ethosomel Gel, Tolnaftate |
| Subjects: | PHARMACY > Pharmaceutics |
| Depositing User: | Ramakrishnan J |
| Date Deposited: | 12 May 2022 09:57 |
| Last Modified: | 12 May 2022 09:57 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/20025 |
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