Hemalatha, P (2019) Adulterants Screening in Herbal Formutaions Using Mordern Analytical Instrument. Masters thesis, College of Pharmacy, Madurai Medical College, Madurai.
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Abstract
High performance thin layer chromatography method was developed for the screening and quantification of Glimepiride, Gliclazide and Glibenclamide present in Herbal Anti-diabetic Formulation as adulterant. The method was developed using silics60 F254 aluminium plate using mobile phase comprising of Ethyl acetate:Petroleum ether: Formic acid (0.4%) (8:2:0.5) and the detection was carried out at 254nm. The developed method can be used to fingerprint the Glimepiride, Gliclazide and Glibenclamide present as adulterant in the Selected Herbal Formulations under optimum parameters. The proposed method has high degree of repeatability and will provide fast and cost-effective control for analysis.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 261715752 |
| Uncontrolled Keywords: | Adulterants Screening, Herbal Formutaions, Mordern Analytical Instrument |
| Subjects: | PHARMACY > Pharmaceutical Chemistry |
| Depositing User: | Ramakrishnan J |
| Date Deposited: | 10 May 2022 09:11 |
| Last Modified: | 10 May 2022 09:11 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/20011 |
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