Kanimozhi, K (2022) Evaluation of 1.5% Quercetin Gel as an Adjunct to Scaling and Root Planing in Chronic Periodontitis Patients: A Clinical and Biochemical study. Masters thesis, J.K.K. Natarajah Dental College and Hospital, Komarapalayam.
Full text not available from this repository.Abstract
INTRODUCTION: To compare the effect of 1.5% Quercetin gel as an adjunct to scaling and root planing in patients with chronic periodontitis by assessing clinical parameters and GCF Interleukin – 6 (IL-6) levels. MATERIALS AND METHODS: In-vitro study was conducted to analyse the four different concentrations of Quercetin against P. gingivalis and 1.5% concentration was formulated as a gel. A randomized, split mouth clinical study with 21 days follow-up was conducted. Chronic periodontitis patients requiring non-surgical periodontal therapy were enrolled and randomly assigned to: (i) Control group with SRP alone (ii) Test group with SRP, followed by 1.5% Quercetin gel placement. All the clinical parameters and biochemical analysis were evaluated at baseline and 21 days after SRP. RESULTS: Twenty patients (10 per group) were included. After 21 days, there was a significant difference in Plaque Index, Gingival Index, Sulcus Bleeding Index and Interleukin - 6 (IL-6) levels in test group than the control group. CONCLUSION: Within the limitations of this study, it can be concluded that 1.5% Quercetin gel showed greater improvement in clinical parameters and reduction in GCF IL-6 levels when used as an adjunct to SRP.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 241913101 |
| Uncontrolled Keywords: | Quercetin, flavonoids, interleulin-6, local drug delivery, periodontitis, non-surgical periodontal therapy, scaling and root planing. |
| Subjects: | DENTAL > Periodontology |
| Depositing User: | Subramani R |
| Date Deposited: | 08 May 2022 15:09 |
| Last Modified: | 13 May 2022 06:11 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/19956 |
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