Comparison of Chorion and Concentrated Growth Factor as Membrane in Management of Bilateral Miller’s Class I and Class II Gingival Recessions in Maxillary Premolars: A Clinical study

Kowsalya, N (2022) Comparison of Chorion and Concentrated Growth Factor as Membrane in Management of Bilateral Miller’s Class I and Class II Gingival Recessions in Maxillary Premolars: A Clinical study. Masters thesis, Adhiparasakthi Dental College and Hospital, Melmaruvathur.

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Abstract

BACKGROUND: Gingival Recession is defined as apical migration of the gingival margin exposing the root surface. The need for recession management is indicated to prevent accumulation of plaque and calculus, prevention of root caries, abrasion and major concern is the patient’s esthetics. There are many techniques used for the management gingival recessions in which Coronally Advanced Flap is the most commonly used technique. Stem cell therapy plays a major role in regeneration of the lost periodontal tissues. These stem cells can be obtained from various intraoral sites and from placental membranes. Once such membrane is Chorion membrane obtained from human placental tissues which is a source of pluripotent stem cells and has other properties such as anti-inflammatory and anti-microbial properties. Growth factors are polypeptide molecules that enhance the healing by modulating the cell responses such as adhesion, attachment and proliferation which can be obtained from human venous blood in the form of Concentrated Growth factor. Use of growth factors will promote healing during regeneration and enhance the clinical outcome. AIM OF THE STUDY: The aim of the study is to compare the efficiency of chorion and concentrated growth factor membrane in the management of bilateral gingival recession in maxillary premolars. MATERIALS AND METHODS: Ten patients with bilateral Miller’s Class I and II gingival recessions in the maxillary and mandibular premolars were included to this study. By coin toss method recessions were randomly treated according to a split-mouth design by means of CAF + Chorion membrane (Group A) and CAF + CGF + CGF membrane (Group B). Clinical outcomes were evaluated at baseline and 3 months after surgery. RESULTS: The mean root coverage (MRC) was 89% and 82%, for Group A and Group B, respectively at 3 months postoperatively. Statistically no difference was demonstrated postoperatively between the two groups in terms of recession height (RH), recession width (RW), Pocket Depth (PD), Clinical Attachment Level (CAL) and Width of Keratinized tissue (WKT) at 3 months. CONCLUSION: This study suggests that Coronally Advanced Flap with Chorion Membrane and Concentrated Growth Factor membrane enhanced periodontal healing and periodontal regeneration.

Item Type: Thesis (Masters)
Additional Information: 241913451
Uncontrolled Keywords: Gingival Recession, Root Coverage, Chorion membrane, Concentrated Growth Factor, CGF Membrane, Coronally Advanced Flap.
Subjects: DENTAL > Periodontology
Depositing User: Subramani R
Date Deposited: 08 May 2022 14:50
Last Modified: 13 May 2022 11:30
URI: http://repository-tnmgrmu.ac.in/id/eprint/19943

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