Myvizhi Selvi, S (2014) Prospective Study in Diabetic Patients to Monitor Adverse Drug Reactions in Various Class of Anti-Diabetic Drugs. Masters thesis, Padmavathi College of Pharmacy and Research Institute, Dharmapuri.
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Abstract
This study indicated the types of adverse reactions occurred during the diabetes mellitus treatment. In this present study I have selected four different grout of medicines available for diabetes treatment e.g, first line therapy for type-1 diabetes is insulin and first line therapy for type 2 diabetes is metformin, followed by pioglitazone and DPP-4 inhibitor sitagliptin. These drugs have various kind of adverse reactions across age and body weight distribution. From our finding it is evident that female gender is more affected by these adverse reactions than male genders. This could be due to hormonal changes occurs in the female compared to male. Further, the new algorithm followed in this study was well in agreement with the conventional analysis by Naranjo’s casualty analysis method. This was further confirmed using kappa test using statistical analysis.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Diabetic Patients ; Monitor Adverse Drug ; Anti-Diabetic Drugs. |
| Subjects: | PHARMACY > Pharmacology |
| Depositing User: | Ravindran C |
| Date Deposited: | 20 Jul 2017 08:38 |
| Last Modified: | 01 Feb 2018 16:47 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/1984 |
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