Arthy, K (2022) Estimation of the Salivary and Serum Nitric Oxide Levels in Patients with Oral Squamous Cell Carcinoma. Masters thesis, K.S.R. Institute of Dental Science and Research, Tiruchengode.
Full text not available from this repository.Abstract
BACKGROUND: Nitric oxide (NO) is a colourless, water soluble and free radical gas with a very short life span of 1-5sec (in vivo). It has divergent role in various cancers including head and neck, breast, lung, gastric, cervical and prostate cancers. NO act as a double edged sword which has both tumorigenic and tumoricidal property. This study was conducted to estimate the salivary and serum nitric oxide (NO) levels in healthy individuals and in histopathologically diagnosed cases of oral squamous cell carcinoma. METHODS: In this study, the salivary and serum NO levels were estimated in 30 healthy subjects and 30 patients with oral squamous cell carcinoma (OSCC) by using griess reagent and multimode reader. RESULTS: Mean and the standard deviation of salivary NO levels in control group was 0.7588± 0.0004 μg/μl while the mean and standard deviation of salivary NO levels of case group was 0.7598 ± 0.0005 μg/μl. The mean and the standard deviation of serum NO levels in control group was 0.7591 ± 0.0003 μg/μl while the mean and the standard deviation of serum NO of case group was 0.7645± 0.0019 μg/μl. CONCLUSION: Our results illustrated that the salivary and serum nitric oxide levels were increased in oral squamous cell carcinoma patients when compared with the healthy individuals. In both case and control group serum nitric oxide levels were elevated when compared to salivary nitric oxide levels.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 241921251 |
| Uncontrolled Keywords: | Oral cancer, nitric oxide, saliva, serum. |
| Subjects: | DENTAL > Oral Pathology and Microbiology |
| Depositing User: | Subramani R |
| Date Deposited: | 08 May 2022 09:04 |
| Last Modified: | 14 May 2022 07:20 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/19786 |
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