Saradhapriya, A (2022) Estimation of Pyruvic Acid and Lactic Acid Levels in Serum and Saliva of Oral Squamous Cell Carcinoma Patients. Masters thesis, K.S.R. Institute of Dental Science and Research, Tiruchengode.
Full text not available from this repository.Abstract
OBJECTIVES: The study was conducted to estimate the serum and salivary pyruvic acid and lactic acid levels in healthy individuals and histopathologically confirmed cases of Oral squamous cell carcinoma. MATERIALS AND METHODS: Thirty clinically and histopathologically confirmed cases of OSCC were included in the study. A control group of 30 age-matched individuals with no systemic diseases were selected. The serum and salivary levels of Pyruvic acid and Lactic acid were measured and the absorbance was read using a spectrophotometer at a wavelength of 540 nm and 390nm respectively. The results were evaluated statistically and discussed. RESULTS: The results were analyzed using T test, Box and whisker analysis. The increase in mean serum and salivary levels of Pyruvic acid and Lactic acid found to be statistically significant respectively when compared to OSCC patients and healthy volunteers (P<0.05). CONCLUSION: Pyruvic acid and lactic acid levels in serum and saliva were found to be increased in OSCC patients. Hence, pyruvic acid and lactic acid can be considered as potential biomarkers for diagnosis as well as in prognosis of OSCC.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 241921252 |
| Uncontrolled Keywords: | Pyruvic acid, Lactic acid, Oral squamous cell carcinoma, Serum. |
| Subjects: | DENTAL > Oral Pathology and Microbiology |
| Depositing User: | Subramani R |
| Date Deposited: | 08 May 2022 09:02 |
| Last Modified: | 14 May 2022 07:16 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/19785 |
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