Senthil Kumar, N (2022) Estimation of Serum and Salivary Albumin and Uric Acid in Patients with Diabetes Mellitus: A Cross Sectional study. Masters thesis, K.S.R. Institute of Dental Science and Research, Tiruchengode.
Full text not available from this repository.Abstract
INTRODUCTION: Diabetes is a potential epidemic in India with more than 62 million individuals currently diagnosed with the disease. Hyperglycemic state of diabetes mellitus produces harmful reactive oxygen species. Antioxidants play an important role in removing and inhibiting the production of free radicals. We designed a study to compare the levels of uric acid and albumin in blood and saliva and determine their interrelationship between diabetic patients and healthy controls. METHODS: 31 patients with type II diabetes and 31 healthy individuals were included in this study to estimate the serum and salivary albumin and uric acid by using bromocresol green and Uricase method respectively. The results were statistically analysed. RESULTS: Mean serum albumin level among the diabetic group was higher (3.99±0.57g/dl) when compared with that of the control group (3.40±0.78g/dl) with statistically significant p value (<0.001). Mean Salivary Albumin of the diabetic group was (0.44±0.91 mg/dl) and for control group was (0.21 ±0.44 mg/dl). This difference was statistically significant. Mean salivary uric acid was higher in diabetic group (2.16±0.57g/dl) than control (1.61±0.73g/dl). This difference was statistically significant. CONCLUSION: Levels of albumin and uric acid in saliva are significantly increased in diabetic individuals when compared with controls. Though similar results were obtained with serum albumin levels, there is no correlation between serum and salivary levels of albumin and uric acid in diabetic individuals. This suggests that salivary levels of albumin and uric acid are independently affected by the disease process.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 241921253 |
| Uncontrolled Keywords: | saliva, serum, Diabetes, albumin, uric acid. |
| Subjects: | DENTAL > Oral Pathology and Microbiology |
| Depositing User: | Subramani R |
| Date Deposited: | 08 May 2022 09:00 |
| Last Modified: | 14 May 2022 07:11 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/19784 |
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