Deenuf Rafeena, M (2022) A Study to Investigate Occurrences of Hearing Loss and Other Hearing Complaints among Head and Neck Malignancy Patients Undergoing Radiotherapy. Masters thesis, Madras Medical College, Chennai.
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Abstract
INTRODUCTION: Head and neck malignancy is the sixth most prevalent type of cancer worldwide. The treatment methods include surgery, chemotherapy, radiotherapy, either as a single modality or in combination. The choice of treatment depends on the size, location of the tumour, staging and patient condition. Irradiation of head and neck tumours are increasingly being used and usually involves the region of temporal bone and Eustachian tube. The auditory apparatus which is sensitive to radiation, is often in the field of irradiation leading to numerous hearing complaints. Sequelae from this treatment and its clinical manifestations may occur during the treatment, just after finishing it or even months after finishing it. The effects of radiation on hearing function have not received much attention unlike other sequelae like xerostomia, mucositis which have been extensively studied. Many patients are developing conductive hearing loss, but SNHL is more disabling to the patient because it has a chronic and often progressive history. MATERIALS AND METHOD: STUDY DESIGN: A prospective study with 25 patients of histologically proven head and neck malignancy receiving radiation therapy is undertaken to study occurrence of hearing loss and other hearing complaint among these population. SOURCE OF DATA: All patients with histologically proven head and neck malignancy visiting the Radiotherapy department at Madras Medical College from June 2020 to September 2021 were taken up for study. METHOD OF COLLECTION OF DATA: SAMPLE SIZE: The sample size chosen is 25. This was estimated based on number of cases being treated in the previous years from our hospital records. INCLUSION CRITERIA: 1. All patients with histologically proven head and neck malignancy. 2. Patient with no significant comorbid condition. 3. Understand the protocol and is able to give informed consent. EXCLUSION CRITERIA: 1. History of hearing or other vestibular disturbance prior to the diagnosis of head and neck malignancy. 2. External or middle ear pathologies on clinical examination. 3. Patients receiving drugs known to cause ototoxicity other than cisplatin. CONCLUSION: ❖ The present study is taken up to determine the incidence of occurrence of hearing loss and other hearing complaints in head and neck malignancy patients undergoing radiotherapy. ❖ Twenty five patients (50 ears) with histologically proven head and neck malignancy where hearing apparatus included in the field of irradiation were the subjects of the study. Standard of care according to the primary has been delivered. All patients had thorough history, clinical examination and audiological evaluation before starting radiotherapy. All the tests were repeated at completion of treatment and at 6 months follow up. ❖ OME is seemingly most common adverse effect after radiotherapy to head and neck malignancy patients. There seems to be a link between the irradiation dosage to the eustachian tube and development of OME. Hence dose titration to eustachian tube should be done to reduce the complication. ❖ Regarding vertigo and tinnitus, during 6 month follow up there was an increased incidence of complaint, hence it signifies chemotherapy induced vestibular toxicity causing dizziness and ringing sound in the ears. Hence dose limitation and rehabilitation plays crucial role. ❖ Hearing loss is still given little recognition and little value. It is one of the chronic problem faced among elderly patients and from this study, population with cancer are even more affected by this. ❖ Concern for the quality of life of patients undergoing cancer treatment is necessarily growing and determination of hearing loss should also form part of such investigation to enable better rehabilitation.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 221914010 |
| Uncontrolled Keywords: | Investigate Occurrences, Hearing Loss, Hearing Complaints, Head and Neck Malignancy Patients, Undergoing Radiotherapy. |
| Subjects: | MEDICAL > Otolaryngology > MEDICAL > Otolaryngology |
| Depositing User: | Subramani R |
| Date Deposited: | 22 Apr 2022 13:46 |
| Last Modified: | 17 Dec 2023 05:18 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/19367 |
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