Karthikeyan, R (2020) Analgesic and Anti-Inflammatory Activity Screening of Ethanolic Extract of Chromolaena Odorata Root. Masters thesis, RVS College of Pharmaceutical Sciences, Coimbatore.
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Abstract
The presented study was an attempt to investigate the Analgesic and Anti-inflammatory activity of extract of Chromolaena odorata roots. The Phytochemical screening showed the presence of Alkaloids, Flavonoids, Glycosides, Steroids, Tanninns and Phenolic compounds which is expected to be responsible for Analgesic and Anti-inflammatory activity. Detailed assessment in the extractive values and the phytochemical analysis revealed that ethanolic extract of Chromolaena odorata is the best extract to be evaluated for the activity. The finding of the present investigation suggests that the ethanolic extract of Chromolaena odorata has potential Analgesic and Anti-inflammatory activity. Toxicity studies do not produce any toxic symptoms on Acute evaluation and during Sub acute toxicity studies the animal groups administered with 1000 mg/kg of the extract showed signs of toxicity. In conclusion the ethanolic extract of Chromolaena odorata are safe upto the dose of 500 mg/kg for continues administration and can be used as Analgesic and Anti-inflammatory agent without any harmful effects. Further studies are required to confirm the exact mechanism behind the Analgesic and Anti-inflammatory activity of Chromolaena odorata ethanolic leaf extract.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 261825652 |
| Uncontrolled Keywords: | Analgesic, Anti-Inflammatory Activity Screening, Ethanolic Extract, Chromolaena Odorata Root |
| Subjects: | PHARMACY > Pharmacology |
| Depositing User: | Ramakrishnan J |
| Date Deposited: | 08 Apr 2022 05:26 |
| Last Modified: | 08 Apr 2022 05:26 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/19199 |
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