Sowmya, S (2022) To Study the Prevalence of Renal Involvement in Patients Receiving Tenofovir Containing Anti Retroviral Therapy. Masters thesis, Madras Medical College, Chennai.
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Abstract
• The Group distribution were PTD is 12.0%, CKD is 12.0%, WRF is 76.0%. • The Age distribution were 21-30 years is 8.0%, 31-40 years is 21.3%, 41-50 years is 37.3%, 51-60 years is 17.3%, >60 years is 16.0%. • The Gender distribution were Female is 46.7%, Male is 53.3%. • The Gender between Groups by Fisher’s exact test were 1 2=0.047, p=0.977>0.05 which shows no statistical significance between Gender and Groups. • The Age between Groups by Fisher’s exact test were 1 2=40.458, p=0.0005<0.01 which shows highly statistical significance between Age and Groups. • The Age between Groups by using Oneway ANOVA were F-value=8.989, pvalue=0.0003<0.01, which shows highly statistical significance difference at p <0.01 level. Followed by Post Hoc Tests - Tukey HSD - Multiple Comparisons table shows Highly Significant at p < 0.01 and No Statistical Significance at p > 0.05 between Groups. • The Duration between Groups by using Oneway ANOVA were F-value=2.514, p value =0.088>0.05, which shows statistical significance difference at p >0.05 level. The CD 4 count between Groups by using Oneway ANOVA were F-value=24.601, pvalue=0.0005<0.01, which shows highly statistical significance difference at p <0.01 level, Followed by Post Hoc Tests – Tukey HSD - Multiple Comparisons table shows Highly Significant at p <0.01 and Statistical Significance at p < 0.05 between Groups. • The Urea between Groups by using Oneway ANOVA were F-value=168.287, pvalue=0.0005<0.01, which shows highly statistical significance difference at p <0.01 level. Followed by Post Hoc Tests - Tukey HSD - Multiple Comparisons table shows Highly Significant at p < 0.01 between Groups. • The Creatinine between Groups by using Oneway ANOVA were F-value=299.429, p-value=0.0005<0.01, which shows highly statistical significance difference at p<0.01 level. Followed by Post Hoc Tests - Tukey HSD - Multiple Comparisons table shows Highly Significant at p < 0.01 between Groups. • The Sodium between Groups by using Oneway ANOVA were F-value=48.164, pvalue=0.0005<0.01, which shows highly statistical significance difference at p <0.01 level. Followed by Post Hoc Tests - Tukey HSD - Multiple Comparisons table shows Highly Significant at p < 0.01 between Groups. The Potassium between Groups by using Oneway ANOVA were F-value=56.251, p-value=0.0005<0.01, which shows highly statistical significance difference at p <0.01 level. Followed by Post Hoc Tests - Tukey HSD - Multiple Comparisons table shows Highly Significant at p < 0.01 between Groups. • The Bicarbonate between Groups by using Oneway ANOVA were F-value=840.992, p-value=0.0005<0.01, which shows highly statistical significance difference at p <0.01 level. Followed by Post Hoc Tests - Tukey HSD - Multiple Comparisons table shows Highly Significant at p < 0.01 and No Statistical Significance at p > 0.05 between Groups. • The Calcium between Groups by using Oneway ANOVA were F-value=370.588, pvalue=0.0005<0.01, which shows highly statistical significance difference at p <0.01 level. Followed by Post Hoc Tests - Tukey HSD - Multiple Comparisons table shows Highly Significant at p < 0.01 and No Statistical Significance at p > 0.05 between Groups. CONCLUSION: • The Group distribution were PTD is 12.0%, CKD is 12.0%, WRF is 76.0%. • The Age distribution were 21-30 years is 8.0%, 31-40 years is 21.3%, 41-50 years is 37.3%, 51-60 years is 17.3%, >60 years is 16.0%. • The Gender distribution were Female is 46.7%, Male is 53.3%. • The Gender between Groups by Fisher’s exact test were ꭓ2=0.047, p=0.977>0.05 which shows no statistical significance between Gender and Groups. LIMITATIONS: In our study only small number of patients (75) were involved and since it was a cross sectional study, the causal relationship could not be identified using a cross sectional analysis. Renal biopsy could not be done because of ethical problems.
| Item Type: | Thesis (Masters) |
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| Additional Information: | 201911020 |
| Uncontrolled Keywords: | Renal Involvement, Patients Receiving, Tenofovir Containing, Anti Retroviral Therapy. |
| Subjects: | MEDICAL > General Medicine > MEDICAL > General Medicine |
| Depositing User: | Thavamani K |
| Date Deposited: | 09 Apr 2022 01:02 |
| Last Modified: | 11 Jan 2024 03:27 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/19170 |
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