Utility of Quick Covid-19 Severity Index in Predicting Early Clinical Decompensation in Hospitalized Patients with Covid-19

Palanisamy, S (2022) Utility of Quick Covid-19 Severity Index in Predicting Early Clinical Decompensation in Hospitalized Patients with Covid-19. Masters thesis, Madras Medical College, Chennai.

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Abstract

BACKGROUND: To assess the performance of quick covid-19 severity index in predicting early clinical decompensation in the form of increased oxygen requirement to 10 L or more, high flow oxygen, non-invasive or invasive ventilation, or death in covid 19 patients which will help in better patient triage as the possibility of next wave is imminent because of considerable variations in the virus. OBJECTIVES: 1. To study the utility of the quick covid-19 severity index in predicting early hospital respiratory failure(within 24 hrs of admission) in patients admitted with covid-19 in Rajiv Gandhi Government General Hospital. 2. To correlate quick covid-19 severity index score with CT severity score in patients admitted with covid-19. METHODS: In this prospective observational study, during admission of covid-19 patients, respiratory rate, pulse oximetry saturation, and oxygen flow rate in L/min via face mask were entered and quick covid-19 severity index score was calculated using these variables. The patients were then assigned to four risk strata and monitored for the next 24 hrs to look for early clinical decompensation. During admission, CT chest was also done which was then correlated with quick covid-19 severity index to see if there was any association between them. RESULTS: Quick covid-19 severity has sensitivity 48.46% ; specificity 91.43% ; positive predictive value 91.30%. negative predictive value 48.85% with significant p-value of < 0.0001 in predicting early clinical decompensation. None of the patients in this study group deteriorated severe enough to put them in invasive or non-invasive ventilation and also no death in this study group during 24 hours of observation. On CT chest grading, 37% of patients had grade 3 pneumonia followed by 31% had grade 2, 20.5% had grade 1 and 11.5% had grade 4. CONCLUSION: The quick covid-19 severity index is a very useful clinical tool that can predict early clinical decompensation of covid-19 patients with high specificity and positive predictive value, even though the score has low sensitivity and low negative predictive value. However, the score did not correlate with the CT severity score.

Item Type: Thesis (Masters)
Additional Information: 201911015
Uncontrolled Keywords: Quick covid-19 severity index, early clinical decompensation, patient triage, CT chest grading.
Subjects: MEDICAL > General Medicine
> MEDICAL > General Medicine
Depositing User: Thavamani K
Date Deposited: 05 Apr 2022 10:51
Last Modified: 10 Jan 2024 16:30
URI: http://repository-tnmgrmu.ac.in/id/eprint/19164

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