Zaburuth Nisha, S (2014) Pharmacognostical, Phytochemical and Hypolipidemic Activity on the Leaves of Operculina Turpethum (L.) Silva Manso. Masters thesis, College of Pharmacy, Madras Medical College, Chennai, Tamil Nadu, India..
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Abstract
Cardiovascular disease (CVD), particularly coronary heart disease (CHD) is the leading cause of medically certified death in both developed as well as developing countries. It is reported that almost 12 million people die of CHD disease each year all over the world. The average onset of CHD is younger among Indians than in other populations around the world. CHD is a disease in which a waxy substance called plaque builds up inside the coronary arteries. Normally these arteries supply oxygen-rich blood to heart muscle. The build up of plaque, limits the flow of oxygen-rich blood through the artery and leads to Angina, Heart attack etc., Cardiovascular disease is one of the leading causes of death worldwide. It is a major risk for hyperlipidemia. A currently available allopathic drug for treating hyperlipidemia occurs with number of side effects and hence people are looking towards the herbal medicine. This paved a vital necessity for finding natural drugs. Operculina turpethum is one such plant with traditional and folklore claims which is useful in the treating Ulcer, Liver disorders, Hyperlipidemia etc., The Pharmacognostical studies on the leaves of Operculina turpethum was carried out first which provides unique features of the plant which may be used to differentiate it from other species. This studies reveal a macroscopical study indicates a characteristic feature in which leaves were ovate, oblong, cordate shaped and green in colour, Anatomical studies revealed the presence of lignified and thick walled xylem cells, vascular bundle towards dorsal side and secondary phloem cells, Powder analysis indicates the presence of anomocytic stomata, unicellular covering trichomes, epidermal cells and parenchyma cells, Lower epidermis of the leaf showed the maximum number of stomata and Epidermis, The above mentioned specific characters might offer reliable clues for the correct identification of this leaf part in crude as well as fragmentary form and also ensures its differentiation from its substitutes and adulterants.
| Item Type: | Thesis (Masters) |
|---|---|
| Uncontrolled Keywords: | Pharmacognostical; Phytochemical; Hypolipidemic Activity; Leaves; Operculina Turpethum ; Silva Manso |
| Subjects: | PHARMACY > Pharmacognosy |
| Depositing User: | Ravindran C |
| Date Deposited: | 19 Jul 2017 09:23 |
| Last Modified: | 19 Jul 2017 09:23 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/1907 |
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