Loganathan, D (2021) Evaluation of Anti-Asthmatic Activity of Aqueous Ethanolic Extract of Cissus Quadrangularis Linn Stem. Masters thesis, Annai J.K.K. Sampoorani Ammal College of Pharmacy, Komarapalayam.
Full text not available from this repository.Abstract
To successfully evaluate the anti asthmatic activity of aqeous ethanolic extract of Cissus quadrangularis linn stem 1. To conduct a literature survey for establishing the relavence of the study. 2. To Collection and authenticate of Cissus quadrangularis linn stem. 3. To successfully extract the coarse dried powder of Cissus quadrangularis linn stem using suitable solvents. Synthetic drugs used for the treatment of asthma and allergy in India but more side effects are reported. Over the centuries, they are using medicinal herbs in daily life and approximately 6000 plants species are known to have medicinal properties in India. As per the literature survey will be expressed medicinal plants and traditional systems of medicines, Ayurveda, Yunani, Siddha and Homeopathy for the treatment of asthma and allergy but no scientific validation. Several literatures are indicated that the herbal drugs have lesser adverse effects when compared to synthetic drugs. The Cissus Quadrangularis L stem is not scientifically validated and which was traditionally using herb. The work provides scientific validation for use of stem against asthma by revealing the chemical compounds may be present in the plant. The present study is attempts to develop a novel plant based antihistamine work through anti-asthmatic drug which will be evaluated by in vitro and in vivo. CONCLUSION: This work will be useful to find new anti asthmatic drug with help of in vitro and in vivo models. Aqueous Ethanolic extract will be possess highly substantial antiasthmatic activity by significantly inhibited the histamine induced broncho constriction of guinea pig representing its H1 receptor antagonistic activity and support the plants by its anti-asthmatic properties. Histamine induced bronchoconstriction is the traditional immunological model of antigen induced airway obstruction. Histamine when inhaled causes hypoxia and leads to convulsion in Guinea pigs and causes very strong smooth muscle contraction, profound hypotension, and capillary dilation in cardiovascular system. A prominent effect caused by histamine leads to severe bronchoconstriction in the Guinea pigs that causes asphyxia and death. Bronchodilators can delay the occurrence of these symptoms. The results of the study confirmed the bronchodilator properties of the plant, justifying its traditional claim in the treatment of asthma. The results will be obtained in the study to be provide basic data for further progress and application of plant.
| Item Type: | Thesis (Masters) |
|---|---|
| Additional Information: | 261925709 |
| Uncontrolled Keywords: | Evaluation, Anti-Asthmatic Activity, Aqueous Ethanolic Extract, Cissus Quadrangularis Linn Stem. |
| Subjects: | PHARMACY > Pharmacology |
| Depositing User: | Ramakrishnan J |
| Date Deposited: | 04 Dec 2021 06:16 |
| Last Modified: | 28 Aug 2022 08:31 |
| URI: | http://repository-tnmgrmu.ac.in/id/eprint/18863 |
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